Institution
University of Texas Medical Branch
Education•Galveston, Texas, United States•
About: University of Texas Medical Branch is a education organization based out in Galveston, Texas, United States. It is known for research contribution in the topics: Population & Virus. The organization has 22033 authors who have published 38268 publications receiving 1517502 citations. The organization is also known as: The University of Texas Medical Branch at Galveston & UTMB.
Topics: Population, Virus, Immune system, Receptor, Poison control
Papers published on a yearly basis
Papers
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TL;DR: This ZIKV amplification was widespread in the Kédougou area, involved several mosquito species as probable vectors, and encompassed all investigated land cover classes except indoor locations within villages.
Abstract: Background
Zika virus (ZIKV; genus Flavivirus, family Flaviviridae) is maintained in a zoonotic cycle between arboreal Aedes spp. mosquitoes and nonhuman primates in African and Asian forests. Spillover into humans has been documented in both regions and the virus is currently responsible for a large outbreak in French Polynesia. ZIKV amplifications are frequent in southeastern Senegal but little is known about their seasonal and spatial dynamics. The aim of this paper is to describe the spatio-temporal patterns of the 2011 ZIKV amplification in southeastern Senegal.
Methodology/Findings
Mosquitoes were collected monthly from April to December 2011 except during July. Each evening from 18∶00 to 21∶00 hrs landing collections were performed by teams of 3 persons working simultaneously in forest (canopy and ground), savannah, agriculture, village (indoor and outdoor) and barren land cover sites. Mosquitoes were tested for virus infection by virus isolation and RT-PCR. ZIKV was detected in 31 of the 1,700 mosquito pools (11,247 mosquitoes) tested: Ae. furcifer (5), Ae. luteocephalus (5), Ae. africanus (5), Ae. vittatus (3), Ae. taylori, Ae. dalzieli, Ae. hirsutus and Ae. metallicus (2 each) and Ae. aegypti, Ae. unilinaetus, Ma. uniformis, Cx. perfuscus and An. coustani (1 pool each) collected in June (3), September (10), October (11), November (6) and December (1). ZIKV was detected from mosquitoes collected in all land cover classes except indoor locations within villages. The virus was detected in only one of the ten villages investigated.
Conclusions/Significance
This ZIKV amplification was widespread in the Kedougou area, involved several mosquito species as probable vectors, and encompassed all investigated land cover classes except indoor locations within villages. Aedes furcifer males and Aedes vittatus were found infected within a village, thus these species are probably involved in the transmission of Zika virus to humans in this environment.
294 citations
TL;DR: The findings indicate that the combined effect on net muscle protein synthesis of carbohydrate and amino acids given together after resistance exercise is roughly equivalent to the sum of the independent effects of either given alone.
Abstract: MILLER, S. L., K. D. TIPTON, D. L. CHINKES, S. E. WOLF, and R. R. WOLFE. Independent and Combined Effects of Amino Acids and Glucose after Resistance Exercise. Med. Sci. Sports Exerc., Vol. 35, No. 3, pp. 449–455, 2003.PurposeThis study was designed to assess the independent and combined eff
294 citations
TL;DR: An experimental model using a static positioning frame, pressure-sensitive film, and a microcomputer-based videodigitizing system was used to measure contact areas and pressures in the wrist.
Abstract: An experimental model using a static positioning frame, pressure-sensitive film (Fuji), and a microcomputer-based videodigitizing system was used to measure contact areas and pressures in the wrist. Contact areas and pressures were compared in a group of wrists between the normal state and with simulated distal radius fracture malunions of varying degrees. In simulated malunions, radial shortening to any degree slightly increased the total contact area in the lunate fossa, and was significant at 2 mm of shortening. By angulating the distal radius more than 20 degrees either palmar or dorsal, there was a dorsal shift in the scaphoid and lunate high pressure areas, and the loads were more concentrated, but there was no change in the load distribution between the scaphoid and lunate. Decreasing the radial inclination shifted the load distribution so that there was more load in the lunate fossa and less load in the scaphoid fossa.
293 citations
TL;DR: It is reported that NF-kappaB activation by lipopolysaccharide and tumor necrosis factor-alpha plays a pivotal role in the suppression of cyp3a4 through interactions of NF-KappaB with the PXR, and NF- kappaB p65 directly interacted with the DNA-binding domain of RXRalpha and may prevent its binding to the consensus DNA sequences, thus inhibiting the transactivation by the PxR.
293 citations
TL;DR: Determination of the relationship between unperturbed extracellular levels and the levels of amino acids in the collected fluids indicates that the concentrations of these amino acids were probably high enough to kill neurons for longer than one hour following impact injury to the spinal cord.
293 citations
Authors
Showing all 22143 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Stuart H. Orkin | 186 | 715 | 112182 |
| Eric R. Kandel | 184 | 603 | 113560 |
| John C. Morris | 183 | 1441 | 168413 |
| Joseph Biederman | 179 | 1012 | 117440 |
| Richard A. Gibbs | 172 | 889 | 249708 |
| Timothy A. Springer | 167 | 669 | 122421 |
| Gabriel N. Hortobagyi | 166 | 1374 | 104845 |
| Roberto Romero | 151 | 1516 | 108321 |
| Charles B. Nemeroff | 149 | 979 | 90426 |
| Peter J. Schwartz | 147 | 647 | 107695 |
| Clifford J. Woolf | 141 | 509 | 86164 |
| Thomas J. Smith | 140 | 1775 | 113919 |
| Edward C. Holmes | 138 | 824 | 85748 |
| Jun Lu | 135 | 1526 | 99767 |
| Henry T. Lynch | 133 | 925 | 86270 |