University of Udine

About: University of Udine is a education organization based out in Udine, Italy. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 6745 authors who have published 20530 publications receiving 669088 citations. The organization is also known as: Università degli Studi di Udine & Universita degli Studi di Udine.

The ATLAS Inner Detector commissioning and calibration

Abstract: The ATLAS Inner Detector is a composite tracking system consisting of silicon pixels, silicon strips and straw tubes in a 2 T magnetic field. Its installation was completed in August 2008 and the detector took part in data-taking with single LHC beams and cosmic rays. The initial detector operation, hardware commissioning and in-situ calibrations are described. Tracking performance has been measured with 7.6 million cosmic-ray events, collected using a tracking trigger and reconstructed with modular pattern-recognition and fitting software. The intrinsic hit efficiency and tracking trigger efficiencies are close to 100%. Lorentz angle measurements for both electrons and holes, specific energy-loss calibration and transition radiation turn-on measurements have been performed. Different alignment techniques have been used to reconstruct the detector geometry. After the initial alignment, a transverse impact parameter resolution of 22.1 +/- 0.9 mu m and a relative momentum resolution sigma (p) /p=(4.83 +/- 0.16)x10(-4) GeV(-1)xp (T) have been measured for high momentum tracks.

Structural correlates of early and late onset Alzheimer's disease: voxel based morphometric study.

Abstract: Objective: To examine the brain structural correlates of age at onset in patients with Alzheimer’s disease. Methods: We studied nine patients with early onset (age ⩽65 years), nine with late onset (age >65) Alzheimer’s disease (EOAD and LOAD, respectively) of mild-moderate severity, and 26 controls who were stratified into younger (YC, age ⩽65, n = 9) and older (OC, age >65, n = 17) subjects. The patients were closely matched for clinical severity: 3/2/3/1 patients had clinical dementia rating of 0.5/1/2/3, respectively, in both the groups. High resolution magnetic resonance images of the brain of the EOAD and YC groups and the LOAD and OC groups were compared on a voxel by voxel basis with statistical parametric mapping to detect areas specifically atrophic. Results: The patients with EOAD showed greater neocortical atrophy at the temporoparietal junction while the patients with LOAD showed greater hippocampal atrophy. The results could not be accounted for by the apolipoprotein E genotype. Conclusions: Since genetic factors are believed to play a relevant pathogenetic role in EOAD and environmental factors in LOAD, genetic and environmental factors may differentially predispose the neocortical and limbic areas to the development of Alzheimer’s neuropathology.

Measurement of the distributions of event-by-event flow harmonics in lead-lead collisions at √SNN = 2.76 TeV with the ATLAS detector at the LHC

Abstract: The distributions of event-by-event harmonic flow coefficients v (n) for n = 2- 4 are measured in = 2.76 TeV Pb + Pb collisions using the ATLAS detector at the LHC. The measurements are performed u ...

Search for electroweak production of supersymmetric particles in final states with two or three leptons at √s=13 TeV with the ATLAS detector

Abstract: A search for the electroweak production of charginos, neutralinos and sleptons decaying into final states involving two or three electrons or muons is presented. The analysis is based on 36.1 fb$^{-1}$ of $\sqrt{s}=13$ TeV proton–proton collisions recorded by the ATLAS detector at the Large Hadron Collider. Several scenarios based on simplified models are considered. These include the associated production of the next-to-lightest neutralino and the lightest chargino, followed by their decays into final states with leptons and the lightest neutralino via either sleptons or Standard Model gauge bosons, direct production of chargino pairs, which in turn decay into leptons and the lightest neutralino via intermediate sleptons, and slepton pair production, where each slepton decays directly into the lightest neutralino and a lepton. No significant deviations from the Standard Model expectation are observed and stringent limits at 95% confidence level are placed on the masses of relevant supersymmetric particles in each of these scenarios. For a massless lightest neutralino, masses up to 580 GeV are excluded for the associated production of the next-to-lightest neutralino and the lightest chargino, assuming gauge-boson mediated decays, whereas for slepton-pair production masses up to 500 GeV are excluded assuming three generations of mass-degenerate sleptons.

The possible role of postprandial hyperglycaemia in the pathogenesis of diabetic complications.

Abstract: It is both common and wise practice to adjust the treatment of diabetic patients to obtain plasma glucose concentrations as close as possible to the "normal range", correcting both postprandial hyperglycaemic spikes and the less increased, but persistently high, plasma glucose concentration between meals. The Diabetes Control and Complications Trials (DCCT) and the United Kingdom Prospective Diabetes Study (UKPDS) have provided evidence that intensive treatment can prevent complications associated with diabetes mellitus. In both studies, effectiveness of hyperglycaemic treatment was assessed by means of the glycated haemoglobin level. This is an integrated measure of both postprandial and fasting hyperglycaemia. The absolute and relative importance of the two conditions, however, could differ depending upon the organ or system suffering from diabetic complications and other more or less known individual factors. This paper aims to emphasize the effects of acute hyperglycaemia, in particular, postprandial hyperglycaemia, on the development of diabetic complications. The role of oxidative stress as a mediator of acute hyperglycaemia is further discussed. More investigation in this area is required so that treatment can be eventually individualised. Perhaps, in some patients, efforts could be concentrated on the control of hyperglycaemic spikes and/or specific organ or system susceptibility to either acute or chronic hyperglycaemia.