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Institution

University of Udine

EducationUdine, Italy
About: University of Udine is a education organization based out in Udine, Italy. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 6745 authors who have published 20530 publications receiving 669088 citations. The organization is also known as: Università degli Studi di Udine & Universita degli Studi di Udine.


Papers
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Journal ArticleDOI
TL;DR: It is hypothesized that a vicious circle between hyperinsulinemia and free radicals could be operating: insulin resistance might cause elevated plasma free radical concentrations, which, in turn, might be responsible for a deterioration of insulin action, with hyperglycemia being a contributory factor.
Abstract: Oxidative stress is an acknowledged pathogenetic mechanism in diabetic complications. Hyperglycemia is a widely known cause of enhanced free radical concentration, whereas oxidative stress involvement in glycemic regulation is still debated. Glucose transport is a cascade of events starting from the interaction of insulin with its own receptor at the plasma membrane and ending with intracellular glucose metabolism. In this complex series of events, each step plays an important role and can be inhibited by a negative effect of oxidative stress. Several studies show that an acute increase in the blood glucose level may impair the physiological homeostasis of many systems in living organisms. The mechanisms through which acute hyperglycemia exerts these effects may be identified in the production of free radicals. It has been suggested that insulin resistance may be accompanied by intracellular production of free radicals. In adipocytes cultured in vitro, insulin increases the production of hydrogen peroxide, which has been shown to mimic the action of insulin. These data allow us to hypothesize that a vicious circle between hyperinsulinemia and free radicals could be operating: insulin resistance might cause elevated plasma free radical concentrations, which, in turn, might be responsible for a deterioration of insulin action, with hyperglycemia being a contributory factor. Data supporting this hypothesis are available. Vitamin E improves insulin action in healthy, elderly, and non-insulin-dependent diabetic subjects. Similar results can be obtained by vitamin C administration.

543 citations

Journal ArticleDOI
TL;DR: A motivation and brief review of the ongoing effort to port Quantum ESPRESSO onto heterogeneous architectures based on hardware accelerators, which will overcome the energy constraints that are currently hindering the way toward exascale computing are presented.
Abstract: Quantum ESPRESSO is an open-source distribution of computer codes for quantum-mechanical materials modeling, based on density-functional theory, pseudopotentials, and plane waves, and renowned for its performance on a wide range of hardware architectures, from laptops to massively parallel computers, as well as for the breadth of its applications. In this paper, we present a motivation and brief review of the ongoing effort to port Quantum ESPRESSO onto heterogeneous architectures based on hardware accelerators, which will overcome the energy constraints that are currently hindering the way toward exascale computing.

543 citations

Book
01 Jan 2006
TL;DR: This book presents the reader, whether an electrical engineering student in power electronics or a design engineer, a selection of power converter control problems and their basic digital solutions, based on the most widespread digital control techniques, to give a basic, introductory knowledge of thedigital control techniques applied to power converters.
Abstract: This book presents the reader, whether an electrical engineering student in power electronics or a design engineer, a selection of power converter control problems and their basic digital solutions, based on the most widespread digital control techniques. The presentation is primarily focused on different applications of the same power converter topology, the half-bridge voltage source inverter, considered both in its single- and three-phase implementation. This is chosen as the test case because, besides being simple and well known, it allows the discussion of a significant spectrum of the most frequently encountered digital control applications in power electronics, from digital pulse width modulation (DPWM) and space vector modulation (SVM), to inverter output current and voltage control, ending with the relatively more complex VSI applications related to the so called smart-grid scenario. This book aims to serve two purposes: (1) to give a basic, introductory knowledge of the digital control techniques applied to power converters; and (2) to raise the interest for discrete time control theory, stimulating new developments in its application to switching power converters.

537 citations

Journal ArticleDOI
TL;DR: Users of anxiolytic benzodiazepines and zopiclone were at increased risk of experiencing a road-traffic accident and should be advised not to drive.

532 citations


Authors

Showing all 6857 results

NameH-indexPapersCitations
M.-Marsel Mesulam15055890772
Francesco Longo14274589859
Georges Aad135112188811
Bobby Samir Acharya1331121100545
G. Della Ricca133159892678
Marina Cobal132107885437
Fernando Barreiro130108283413
Saverio D'Auria129114283684
Jean-Francois Grivaz128132297758
Evgeny Starchenko12886475913
Muhammad Alhroob12788071982
Michele Pinamonti12684669328
Reisaburo Tanaka12696769849
Kerim Suruliz12679569456
Kate Shaw12584170087
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202350
2022142
20211,338
20201,388
20191,223
20181,102