Institution
University of Westminster
Education•London, United Kingdom•
About: University of Westminster is a education organization based out in London, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 2944 authors who have published 8426 publications receiving 200236 citations. The organization is also known as: Westminster University & Royal Polytechnic Institution.
Topics: Population, Context (language use), Politics, Tourism, European union
Papers published on a yearly basis
Papers
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TL;DR: The Satisfaction With Life Scale (SWLS) is one of the most widely used scales for the measurement of subjective well-being across the globe, but no satisfactory version exists for use among Malay-speaking populations as discussed by the authors.
Abstract: The Satisfaction With Life Scale (SWLS) is one of the most widely used scales for the measurement of subjective well-being across the globe, but no satisfactory version exists for use among Malay-speaking populations. The present study reports on the translation of a new Malay SWLS and examines its psychometric properties in a community sample of 816 Malay and 738 Chinese participants from Malaysia. Results showed that the Malay SWLS had good internal consistency (Cronbach’s α = 0.83). Confirmatory factor analysis showed support for a unidimensional factor structure which remained invariant across sex and ethnic group. These results suggest that the Malay SWLS is a valid and reliable measure of life satisfaction for Malay-speaking samples, and extends the list of available scales for measuring subjective well-being among such groups.
72 citations
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TL;DR: In this article, the authors used CGTase from Bacillus circulans strain to produce cyclodextrin glycosyltransferase (EC 2.4.1.19) and found that the reaction rate of this reaction was dependent on the nature of the organic solvent used.
71 citations
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TL;DR: Clinical data is provided indicating that the glutamine–proline regulatory axis plays an important role in the aggressive subclass of luminal BC and is therefore a potential therapeutic target.
Abstract: Altered cellular metabolism is a hallmark of cancer and some are reliant on glutamine for sustained proliferation and survival. We hypothesise that the glutamine–proline regulatory axis has a key role in breast cancer (BC) in the highly proliferative classes. Glutaminase (GLS), pyrroline-5-carboxylate synthetase (ALDH18A1), and pyrroline-5-carboxylate reductase 1 (PYCR1) were assessed at DNA/mRNA/protein levels in large, well-characterised cohorts. Gain of PYCR1 copy number and high PYCR1 mRNA was associated with Luminal B tumours. High ALDH18A1 and high GLS protein expression was observed in the oestrogen receptor (ER)+/human epidermal growth factor receptor (HER2)– high proliferation class (Luminal B) compared with ER+/HER2– low proliferation class (Luminal A) (P=0.030 and P=0.022 respectively), however this was not observed with mRNA. Cluster analysis of the glutamine–proline regulatory axis genes revealed significant associations with molecular subtypes of BC and patient outcome independent of standard clinicopathological parameters (P=0.012). High protein expression of the glutamine–proline enzymes were all associated with high MYC protein in Luminal B tumours only (P<0.001). We provide comprehensive clinical data indicating that the glutamine–proline regulatory axis plays an important role in the aggressive subclass of luminal BC and is therefore a potential therapeutic target.
71 citations
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TL;DR: In this paper, the authors analyse the different activities within the value chain of organic cotton production in India to understand where, and how, value is added at each stage of converting a cotton crop into a textile and then into a final item of clothing.
71 citations
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TL;DR: Zhang et al. as discussed by the authors examined the relationship between neighbourhood natural outdoor environments and individuals' mental health in Guangzhou, China, using a combination of questionnaire survey data, streetscape and remote-sensing metrics, and multilevel structural equation modelling.
71 citations
Authors
Showing all 3028 results
Name | H-index | Papers | Citations |
---|---|---|---|
Barbara J. Sahakian | 145 | 612 | 69190 |
Peter B. Jones | 145 | 1857 | 94641 |
Andrew Steptoe | 137 | 1003 | 73431 |
Robert West | 112 | 1061 | 53904 |
Aldo R. Boccaccini | 103 | 1234 | 54155 |
Kevin Morgan | 95 | 655 | 49644 |
Shaogang Gong | 92 | 430 | 31444 |
Thomas A. Buchanan | 91 | 349 | 48865 |
Mauro Perretti | 90 | 497 | 28463 |
Jimmy D. Bell | 88 | 589 | 25983 |
Andrew D. McCulloch | 75 | 358 | 19319 |
Mark S. Goldberg | 73 | 235 | 18067 |
Dimitrios Buhalis | 72 | 316 | 23830 |
Ali Mobasheri | 69 | 370 | 14642 |
Michael E. Boulton | 69 | 331 | 23747 |