Zhejiang Gongshang University

About: Zhejiang Gongshang University is a education organization based out in Hangzhou, China. It is known for research contribution in the topics: Computer science & Chemistry. The organization has 8258 authors who have published 7670 publications receiving 90296 citations. The organization is also known as: Zhèjiāng Gōngshāng Dàxué.

Two-Party Quantum Private Comparison with Five-Qubit Entangled States

Abstract: In this paper, a two-party quantum private comparison (QPC) protocol is proposed by using five-qubit entangled states as the quantum resource. The proposed protocol needs the help from a semi-honest third party (TP), who is allowed to misbehave on his own but not allowed to conspire with the adversary including the dishonest user. The proposed protocol has the following distinct features: (1) One five-qubit entangled state can be used to achieve the equality comparison of two bits in each round of comparison; (2) Neither unitary operations nor quantum entanglement swapping technology is needed, both of which may consume expensive quantum devices; (3) Only Bell measurements and single-particle measurements are employed, both of which can be realized with current quantum technologies; (4) The security toward both the outside attack and the participant attack can be guaranteed; (5) The private information of two parties is not leaked out to TP.

Cobalamin (Vitamin B12) Induced a Shift in Microbial Composition and Metabolic Activity in an in vitro Colon Simulation

Abstract: Cobalamin deficiency is believed to be related to disturbances in cell division, neuropathy, nervous system disease and pernicious anemia. Elderly people are usually advised to supplement their diets with cobalamin. As cobalamin has several forms, the effects of different forms of cobalamin on gut microbiota were investigated in this study. After 7 days of supplementation, methylcobalamin had reduced the diversity of gut microbiota compared to that in the control and cyanocobalamin groups. After supplementation with methylcobalamin, the percentage of Acinetobacter spp. had increased to 45.54%, while the percentages of Bacteroides spp., Enterobacteriaceae spp. and Ruminococcaceae spp. had declined to 11.15, 9.34, and 2.69%, respectively. However, cyanocobalamin had different influences on these bacteria. Both cobalamins increased the amount of short-chain fatty acids, particularly butyrate and propionic acid. The cyanocobalamin group showed increased activity of cellulase compared with that in the other two groups. According to CCA and PICRUSt analysis, methylcobalamin had a positive correlation with Pseudomonas bacteria, propionic acid, and butyrate. Methylcobalamin promoted lipid, terpenoid, and polyketide metabolism by gut bacteria, promoted the degradation of exogenous substances, and inhibited the synthesis of transcription factors and secondary metabolites. Our results indicate that the various forms of cobalamin in the food industry should be monitored and regulated, because the two types of cobalamin had different effects on the gut microbiome and on microbial metabolism, although they have equal bio-activity in humans. Given the effects of methylcobalamin on gut microbiota and microbial metabolism, methylcobalamin supplementation should be suggested as the first option.