Journal ArticleDOI
A general approach to DNA-programmable atom equivalents
Chuan Zhang,Robert J. Macfarlane,Kaylie L. Young,Chung Hang Jonathan Choi,Liangliang Hao,Evelyn Auyeung,Guoliang Liu,Xiaozhu Zhou,Chad A. Mirkin +8 more
TLDR
By coating nanoparticles protected with aliphatic ligands with an azide-bearing amphiphilic polymer, followed by the coupling of DNA to the polymer using strain-promoted azide -alkyne cycloaddition, nanoparticles bearing a high-density shell of nucleic acids can be created regardless of nanoparticle composition.Abstract:
Nanoparticles can be combined with nucleic acids to programme the formation of three-dimensional colloidal crystals where the particles' size, shape, composition and position can be independently controlled. However, the diversity of the types of material that can be used is limited by the lack of a general method for preparing the basic DNA-functionalized building blocks needed to bond nanoparticles of different chemical compositions into lattices in a controllable manner. Here we show that by coating nanoparticles protected with aliphatic ligands with an azide-bearing amphiphilic polymer, followed by the coupling of DNA to the polymer using strain-promoted azide-alkyne cycloaddition (also known as copper-free azide-alkyne click chemistry), nanoparticles bearing a high-density shell of nucleic acids can be created regardless of nanoparticle composition. This method provides a route to a virtually endless class of programmable atom equivalents for DNA-based colloidal crystallization.read more
Citations
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Journal ArticleDOI
Dynamic tuning of DNA-nanoparticle superlattices by molecular intercalation of double helix.
TL;DR: A novel strategy for modulation of interparticle distances in DNA linked 3D self-assembled NP lattices by molecular intercalator permits the creation of reconfigurable and thermally stable superlattices, which could lead to tunable and functionally responsive materials.
Journal ArticleDOI
DNA nanostructure-directed assembly of metal nanoparticle superlattices.
TL;DR: This focused review discusses the DNA structure-directed nanoparticle assemblies covering the wide range of different one-, two-, and three-dimensional systems.
Journal ArticleDOI
Nanoparticles Self-Assembly Driven by High Affinity Repeat Protein Pairing
K. L. Gurunatha,Agathe C. Fournier,Agathe Urvoas,Marie Valerio-Lepiniec,Valérie Marchi,Philippe Minard,Erik Dujardin +6 more
TL;DR: This work reports on the protein-directed assembly of gold nanoparticles using purpose-designed artificial repeat proteins having a rigid but modular 3D architecture, and demonstrates that the aggregates are reversibly disassembled by an excess of one free protein.
Journal ArticleDOI
Rational design of nanomaterials from assembly and reconfigurability of polymer-tethered nanoparticles
TL;DR: A brief review of the recent advances in assembly and reconfigurability of polymer-based nanostructures can be found in this article, where the authors highlight the role of computer simulation in discovering the fundamental principles of assembly science and providing critical design tools for assembly engineering of complex polymeric materials.
Journal ArticleDOI
Controlled Assembly of Plasmonic Nanoparticles: From Static to Dynamic Nanostructures.
TL;DR: In this paper, a review of recent advances in bottom-up chemical strategies toward the well-controlled assembly of plasmonic nanoparticles, including multicomponent and multifunctional systems, is presented.
References
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TL;DR: A review of gold nanoparticles can be found in this article, where the most stable metal nanoparticles, called gold colloids (AuNPs), have been used for catalysis and biology applications.
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Semiconductor Clusters, Nanocrystals, and Quantum Dots
TL;DR: In this article, the authors focus on the properties of quantum dots and their ability to join the dots into complex assemblies creates many opportunities for scientific discovery, such as the ability of joining the dots to complex assemblies.
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A DNA-based Method for Rationally Assembling Nanoparticles Into Macroscopic Materials
TL;DR: A method for assembling colloidal gold nanoparticles rationally and reversibly into macroscopic aggregates by using the specificity of DNA interactions to direct the interactions between particles of different size and composition is described.
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In vivo cancer targeting and imaging with semiconductor quantum dots
TL;DR: Sensitive and multicolor fluorescence imaging of cancer cells under in vivo conditions are achieved and a whole-body macro-illumination system with wavelength-resolved spectral imaging is integrated for efficient background removal and precise delineation of weak spectral signatures.
Journal ArticleDOI
Selective Colorimetric Detection of Polynucleotides Based on the Distance-Dependent Optical Properties of Gold Nanoparticles
TL;DR: A highly selective, colorimetric polynucleotide detection method based on mercaptoalkyloligonucleotide-modified gold nanoparticle probes is reported, which can detect about 10 femtomoles of an oligonucleotide.