Journal ArticleDOI
A rating scale for mania: reliability, validity and sensitivity.
TLDR
The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently, and also correlated with the number of days of subsequent stay in hospital.Abstract:
An eleven item clinician-administered Mania Rating Scale (MRS) is introduced, and its reliability, validity and sensitivity are examined. There was a high correlation between the scores of two independent clinicians on both the total score (0.93) and the individual item scores (0.66 to 0.92). The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently. The score also correlated with the number of days of subsequent stay in hospital. It was able to differentiate statistically patients before and after two weeks of treatment and to distinguish levels of severity based on the global rating.read more
Citations
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Journal ArticleDOI
Quetiapine or haloperidol as monotherapy for bipolar mania--a 12-week, double-blind, randomised, parallel-group, placebo-controlled trial.
TL;DR: The efficacy and tolerability profile of haloperidol (including its propensity for EPS) supported study validity and quetiapine was effective and well tolerated.
Journal ArticleDOI
Elevated striatal and decreased dorsolateral prefrontal cortical activity in response to emotional stimuli in euthymic bipolar disorder: no associations with psychotropic medication load
Stefanie Hassel,Jorge R. C. Almeida,Jorge R. C. Almeida,Natalie Z. Kerr,Sharon Nau,Cecile D. Ladouceur,Kate Fissell,David J. Kupfer,Mary L. Phillips +8 more
TL;DR: No relationship between medication load and abnormal neural activity in bipolar individuals suggests that the findings may reflect pathophysiologic mechanisms of the illness rather than medication confounds, and future studies should examine whether this pattern of abnormal neuralactivity could distinguish bipolar from unipolar depression.
Journal ArticleDOI
Treatment-Resistant Bipolar Depression: A STEP-BD Equipoise Randomized Effectiveness Trial of Antidepressant Augmentation With Lamotrigine, Inositol, or Risperidone
Andrew A. Nierenberg,Michael J. Ostacher,Joseph R. Calabrese,Terence A. Ketter,Lauren B. Marangell,David J. Miklowitz,Sachiko Miyahara,Mark S. Bauer,Michael E. Thase,Stephen R. Wisniewski,Gary S. Sachs +10 more
TL;DR: Post hoc secondary analyses suggest that lamotrigine may be superior to inositol and risperidone in improving treatment-resistant bipolar depression.
Journal ArticleDOI
Aripiprazole in the treatment of acute manic or mixed episodes in patients with bipolar I disorder: a 3-week placebo-controlled study.
Gary S. Sachs,Raymond Sanchez,Ronald N. Marcus,Elyse Stock,Robert D. McQuade,William H. Carson,Neveen Abou-Gharbia,Cheryl Impellizzeri,Stephen Kaplita,Linda Rollin,Taro Iwamoto +10 more
TL;DR: Aripiprazole demonstrated superior efficacy to placebo in the treatment of patients with bipolar I disorder presenting with acute manic or mixed episodes, and exhibited a favourable safety and tolerability profile.
Journal ArticleDOI
Randomized, Placebo-Controlled Trial of Mixed Amphetamine Salts for Symptoms of Comorbid ADHD in Pediatric Bipolar Disorder After Mood Stabilization With Divalproex Sodium
TL;DR: Pediatric patients with bipolar disorder and concurrent ADHD can be safely and effectively treated with mixed amphetamine salts after their manic symptoms are stabilized with divalproex sodium.
References
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Book
Nonparametric statistics for the behavioral sciences
TL;DR: This is the revision of the classic text in the field, adding two new chapters and thoroughly updating all others as discussed by the authors, and the original structure is retained, and the book continues to serve as a combined text/reference.
Journal ArticleDOI
A rating scale for depression
TL;DR: The present scale has been devised for use only on patients already diagnosed as suffering from affective disorder of depressive type, used for quantifying the results of an interview, and its value depends entirely on the skill of the interviewer in eliciting the necessary information.
Journal ArticleDOI
The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Journal ArticleDOI
Diagnostic criteria for use in psychiatric research.
John P. Feighner,Eli Robins,Samuel B. Guze,Robert A. Woodruff,George Winokur,Rodrigo A. Munoz +5 more
TL;DR: Diagnostic criteria for 14 psychiatric illnesses along with the validating evidence for these diagnostic categories comes from workers outside the authors' group as well as from those within; it consists of studies of both outpatients and inpatients, of family studies, and of follow-up studies.