Journal ArticleDOI
A rating scale for mania: reliability, validity and sensitivity.
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TLDR
The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently, and also correlated with the number of days of subsequent stay in hospital.Abstract:
An eleven item clinician-administered Mania Rating Scale (MRS) is introduced, and its reliability, validity and sensitivity are examined. There was a high correlation between the scores of two independent clinicians on both the total score (0.93) and the individual item scores (0.66 to 0.92). The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently. The score also correlated with the number of days of subsequent stay in hospital. It was able to differentiate statistically patients before and after two weeks of treatment and to distinguish levels of severity based on the global rating.read more
Citations
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Standardised rating scales in psychiatry: methodological basis, their possibilities and limitations and descriptions of important rating scales.
TL;DR: Standardized rating scales are an important tool to improve the assessment of psychopathological symptoms in terms of validity and reliability, and especially observer-rated scales are of primary importance in this respect.
Journal ArticleDOI
Immune parameters in rapid cycling bipolar patients before and after lithium treatment.
TL;DR: Data suggest that rapid cycling bipolar patients may have mild immune activation which seems to normalize with lithium treatment, and lithium treatment increased IL-2, SIL-2RS and SIL-6RS in normal volunteers.
Journal ArticleDOI
SSRIs as mood stabilizers for Bipolar II Disorder? A proof of concept study
TL;DR: This proof of concept study finds preliminary support for the potential utility of SSRIs in managing Bipolar II Disorder, with clear improvements in depression and impairment and some suggested benefit for hypomania.
Journal ArticleDOI
Clinical predictors of response to lamotrigine and gabapentin monotherapy in refractory affective disorders.
Gabriela V Obrocea,Robert M Dunn,Mark A. Frye,Terence A. Ketter,David A. Luckenbaugh,Gabriele S. Leverich,Andrew M. Speer,Elizabeth A. Osuch,Kamal Jajodia,Robert M. Post +9 more
TL;DR: Preliminary data in a treatment refractory subgroup may help in the further definition of the range of clinical utility of these widely used anticonvulsants.
Journal ArticleDOI
Impaired probabilistic reversal learning in youths with mood and anxiety disorders
Daniel P. Dickstein,Elizabeth Finger,Melissa A. Brotman,Brendan A. Rich,Daniel S. Pine,James R. Blair,Ellen Leibenluft +6 more
TL;DR: The results suggest that reversal learning deficits are present in youths with BD and possibly those with MDD, and further work is necessary to elucidate the specificity of neural mechanisms underlying such behavioral deficits.
References
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Book
Nonparametric statistics for the behavioral sciences
TL;DR: This is the revision of the classic text in the field, adding two new chapters and thoroughly updating all others as discussed by the authors, and the original structure is retained, and the book continues to serve as a combined text/reference.
Journal ArticleDOI
A rating scale for depression
TL;DR: The present scale has been devised for use only on patients already diagnosed as suffering from affective disorder of depressive type, used for quantifying the results of an interview, and its value depends entirely on the skill of the interviewer in eliciting the necessary information.
Journal ArticleDOI
The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Journal ArticleDOI
Diagnostic criteria for use in psychiatric research.
John P. Feighner,Eli Robins,Samuel B. Guze,Robert A. Woodruff,George Winokur,Rodrigo A. Munoz +5 more
TL;DR: Diagnostic criteria for 14 psychiatric illnesses along with the validating evidence for these diagnostic categories comes from workers outside the authors' group as well as from those within; it consists of studies of both outpatients and inpatients, of family studies, and of follow-up studies.