Journal ArticleDOI
A rating scale for mania: reliability, validity and sensitivity.
TLDR
The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently, and also correlated with the number of days of subsequent stay in hospital.Abstract:
An eleven item clinician-administered Mania Rating Scale (MRS) is introduced, and its reliability, validity and sensitivity are examined. There was a high correlation between the scores of two independent clinicians on both the total score (0.93) and the individual item scores (0.66 to 0.92). The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently. The score also correlated with the number of days of subsequent stay in hospital. It was able to differentiate statistically patients before and after two weeks of treatment and to distinguish levels of severity based on the global rating.read more
Citations
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Bilateral decrease in ventrolateral prefrontal cortex activation during motor response inhibition in mania.
Pascale Mazzola-Pomietto,Arthur Kaladjian,Jean-Michel Azorin,Jean-Luc Anton,Régine Jeanningros +4 more
TL;DR: The data suggest that response inhibition in mania is associated with a lack of engagement of the bilateral VLPFC, which is known to play a primary role in the suppression of irrelevant responses, and might give clues to understanding the pathophysiology of disinhibition and impulsivity that characterize mania.
Journal ArticleDOI
Cognitive effects of adjunctive N-acetyl cysteine in psychosis
Marta Rapado-Castro,Seetal Dodd,Ashley I. Bush,Gin S Malhi,David Skvarc,Z X On,Michael Berk,Olivia M Dean +7 more
TL;DR: NAC may have an impact on cognitive performance in psychosis, as a significant improvement in working memory was observed in the NAC-treated group compared with placebo; however, these preliminary data require replication.
Journal ArticleDOI
Facial emotion processing in acutely ill and euthymic patients with pediatric bipolar disorder
TL;DR: Evidence of both state-of-illness and trait-related deficits in emotion processing in PBD is found, and treatments are needed to better reduce this impairment and to reduce its developmental impact on interpersonal functioning.
Journal ArticleDOI
A functional MRI study of Theory of Mind in euthymic bipolar disorder patients
Gin S Malhi,Gin S Malhi,Jim Lagopoulos,Jim Lagopoulos,Pritha Das,Pritha Das,Kirsteen Moss,Kirsteen Moss,Michael Berk,Michael Berk,Carissa Coulston,Carissa Coulston +11 more
TL;DR: The findings of this novel neuroimaging study suggest that in a social context, euthymic bipolar patients are perhaps constrained in their ability to mentalize fully, and furthermore cannot reliably adopt an alternate cognitive perspective when appropriate.
Journal ArticleDOI
Ketamine modulates hippocampal neurochemistry and functional connectivity: a combined magnetic resonance spectroscopy and resting-state fMRI study in healthy volunteers.
Nina V. Kraguljac,Michael A. Frölich,Steve Tran,David White,Nona Nichols,Alexander Barton-McArdle,Meredith A. Reid,Mark Bolding,Adrienne C. Lahti +8 more
TL;DR: The data empirically support that hippocampal glutamatergic elevation and resting-state network alterations may arise from NMDAR hypofunction and establish a proof of principle whereby experimental modelling of a disorder can help mechanistically integrate distinct neuroimaging abnormalities in schizophrenia.
References
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Book
Nonparametric statistics for the behavioral sciences
TL;DR: This is the revision of the classic text in the field, adding two new chapters and thoroughly updating all others as discussed by the authors, and the original structure is retained, and the book continues to serve as a combined text/reference.
Journal ArticleDOI
A rating scale for depression
TL;DR: The present scale has been devised for use only on patients already diagnosed as suffering from affective disorder of depressive type, used for quantifying the results of an interview, and its value depends entirely on the skill of the interviewer in eliciting the necessary information.
Journal ArticleDOI
The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Journal ArticleDOI
Diagnostic criteria for use in psychiatric research.
John P. Feighner,Eli Robins,Samuel B. Guze,Robert A. Woodruff,George Winokur,Rodrigo A. Munoz +5 more
TL;DR: Diagnostic criteria for 14 psychiatric illnesses along with the validating evidence for these diagnostic categories comes from workers outside the authors' group as well as from those within; it consists of studies of both outpatients and inpatients, of family studies, and of follow-up studies.