Journal ArticleDOI
A rating scale for mania: reliability, validity and sensitivity.
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TLDR
The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently, and also correlated with the number of days of subsequent stay in hospital.Abstract:
An eleven item clinician-administered Mania Rating Scale (MRS) is introduced, and its reliability, validity and sensitivity are examined. There was a high correlation between the scores of two independent clinicians on both the total score (0.93) and the individual item scores (0.66 to 0.92). The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently. The score also correlated with the number of days of subsequent stay in hospital. It was able to differentiate statistically patients before and after two weeks of treatment and to distinguish levels of severity based on the global rating.read more
Citations
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Quantitative assessment of attribution of intentions to others in schizophrenia using an ecological video-based task: a comparison with manic and depressed patients.
Nadine Bazin,Eric Brunet-Gouet,Catherine Bourdet,Nadja Kayser,Bruno Falissard,Marie-Christine Hardy-Baylé,Christine Passerieux +6 more
TL;DR: Results show that tasks based on more ecological stimuli are powerful enough to detect theory-of-mind abnormalities in pathological populations such as schizophrenic patients.
Journal ArticleDOI
Phenytoin as an Antimanic Anticonvulsant: A Controlled Study
TL;DR: Significantly more improvement was observed in the patients receiving phenytoin and blockade of voltage-activated sodium channels may be a common therapeutic mechanism of many anticonvulsants given for mania, and pheny toin may beA therapeutic option for some manic patients.
Journal ArticleDOI
Acute mood and thyroid stimulating hormone effects of transcranial magnetic stimulation in major depression
Martin P. Szuba,John P. O'Reardon,Anil S Rai,Judith Snyder-Kastenberg,Jay D. Amsterdam,David R. Gettes,Eric M. Wassermann,Dwight L. Evans +7 more
TL;DR: This blinded, placebo-controlled trial documents that individual rTMS sessions can acutely elevate mood and stimulate TSH release in patients experiencing major depressive episodes.
Journal ArticleDOI
Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: an in vivo 1 H MRS study
Benicio N. Frey,Benicio N. Frey,Jeffrey A. Stanley,Fabiano G. Nery,Fabiano G. Nery,E. Serap Monkul,E. Serap Monkul,Mark Nicoletti,Mark Nicoletti,Hua Hsuan Chen,John P. Hatch,Sheila C. Caetano,Sheila C. Caetano,Oswaldo Ortiz,Flávio Kapczinski,Jair C. Soares,Jair C. Soares +16 more
TL;DR: These findings provide further evidence that the pathophysiology of BD involves impairment in the DLPFC, and can be interpreted as evidence for reduced cellular energy and phospholipid metabolism, consistent with the hypothesis of mitochondrial dysfunction in BD.
Journal ArticleDOI
Serotonin transporter gene associated with lithium prophylaxis in mood disorders.
TL;DR: 5-HTTLPR variants may be a possible influencing factor for the prophylactic efficacy of lithium in mood disorders and subjects with the s/s variant showed a worse response compared to both l/s and l/l variants.
References
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Book
Nonparametric statistics for the behavioral sciences
TL;DR: This is the revision of the classic text in the field, adding two new chapters and thoroughly updating all others as discussed by the authors, and the original structure is retained, and the book continues to serve as a combined text/reference.
Journal ArticleDOI
A rating scale for depression
TL;DR: The present scale has been devised for use only on patients already diagnosed as suffering from affective disorder of depressive type, used for quantifying the results of an interview, and its value depends entirely on the skill of the interviewer in eliciting the necessary information.
Journal ArticleDOI
The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Journal ArticleDOI
Diagnostic criteria for use in psychiatric research.
John P. Feighner,Eli Robins,Samuel B. Guze,Robert A. Woodruff,George Winokur,Rodrigo A. Munoz +5 more
TL;DR: Diagnostic criteria for 14 psychiatric illnesses along with the validating evidence for these diagnostic categories comes from workers outside the authors' group as well as from those within; it consists of studies of both outpatients and inpatients, of family studies, and of follow-up studies.