Journal ArticleDOI
A rating scale for mania: reliability, validity and sensitivity.
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TLDR
The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently, and also correlated with the number of days of subsequent stay in hospital.Abstract:
An eleven item clinician-administered Mania Rating Scale (MRS) is introduced, and its reliability, validity and sensitivity are examined. There was a high correlation between the scores of two independent clinicians on both the total score (0.93) and the individual item scores (0.66 to 0.92). The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently. The score also correlated with the number of days of subsequent stay in hospital. It was able to differentiate statistically patients before and after two weeks of treatment and to distinguish levels of severity based on the global rating.read more
Citations
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Low Cerebrospinal Fluid Glutamate and Glycine in Refractory Affective Disorder
TL;DR: It is suggested that in patients with refractory affective disorder, excitatory amino acids are dysregulated, as exemplified both by the decreased CSF glutamate and glycine and their high intercorrelation compared to controls.
Journal ArticleDOI
Progressive behavioral response to repeated d-amphetamine challenge: further evidence for sensitization in humans
TL;DR: Eye-blink rate and increased motor activity/energy ratings progressively increased following each challenge with the third amphetamine dose response significantly greater than all other conditions 4 hours postadministration, providing further evidence for sensitization of some amphetamine-induced behaviors in human subjects.
Journal ArticleDOI
A multicenter tractography study of deep white matter tracts in bipolar I disorder: psychotic features and interhemispheric disconnectivity.
Samuel Sarrazin,Cyril Poupon,Julia Linke,Michèle Wessa,Mary L. Phillips,Marine Delavest,Amelia Versace,Jorge R. C. Almeida,Pamela Guevara,D. Duclap,Edouard Duchesnay,Jean-François Mangin,Katia Le Dudal,Claire Daban,Nora Hamdani,Marc Antoine D'Albis,Marion Leboyer,Josselin Houenou +17 more
TL;DR: In this multicenter sample of bipolar I disorder patients, BPI patients had reduced WM integrity in interhemispheric, limbic, and arcuate WM tracts, highlighting the existence of an anatomic disconnectivity in BPI and underscoring a role for interhemipheric disconnectedivity in the pathophysiological features of psychosis.
Journal ArticleDOI
Brain-derived neurotrophic factor serum levels before and after treatment for acute mania.
Juliana Tramontina,Ana Cristina Andreazza,Márcia Kauer-Sant'Anna,Laura Stertz,Julia Goi,Fabria Chiarani,Flávio Kapczinski +6 more
TL;DR: The results showed that BDNF levels were decreased in BD patients during mania when compared to controls but this difference was no longer significant after treatment, and a sharp increase was found after treatment of the episode of acute mania.
Journal ArticleDOI
Characterizing cognitive heterogeneity on the schizophrenia-bipolar disorder spectrum
T E Van Rheenen,Kathryn E. Lewandowski,Eric J. Tan,Luz H. Ospina,Dost Öngür,Erica Neill,Caroline Gurvich,Christos Pantelis,Anil K. Malhotra,Susan L. Rossell,Katherine E. Burdick +10 more
TL;DR: Quantitative SZ–BD cognitive differences commonly seen using group averages did not hold when cognitive heterogeneity was factored into the sample.
References
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Book
Nonparametric statistics for the behavioral sciences
TL;DR: This is the revision of the classic text in the field, adding two new chapters and thoroughly updating all others as discussed by the authors, and the original structure is retained, and the book continues to serve as a combined text/reference.
Journal ArticleDOI
A rating scale for depression
TL;DR: The present scale has been devised for use only on patients already diagnosed as suffering from affective disorder of depressive type, used for quantifying the results of an interview, and its value depends entirely on the skill of the interviewer in eliciting the necessary information.
Journal ArticleDOI
The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Journal ArticleDOI
Diagnostic criteria for use in psychiatric research.
John P. Feighner,Eli Robins,Samuel B. Guze,Robert A. Woodruff,George Winokur,Rodrigo A. Munoz +5 more
TL;DR: Diagnostic criteria for 14 psychiatric illnesses along with the validating evidence for these diagnostic categories comes from workers outside the authors' group as well as from those within; it consists of studies of both outpatients and inpatients, of family studies, and of follow-up studies.