Journal ArticleDOI
A rating scale for mania: reliability, validity and sensitivity.
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TLDR
The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently, and also correlated with the number of days of subsequent stay in hospital.Abstract:
An eleven item clinician-administered Mania Rating Scale (MRS) is introduced, and its reliability, validity and sensitivity are examined. There was a high correlation between the scores of two independent clinicians on both the total score (0.93) and the individual item scores (0.66 to 0.92). The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently. The score also correlated with the number of days of subsequent stay in hospital. It was able to differentiate statistically patients before and after two weeks of treatment and to distinguish levels of severity based on the global rating.read more
Citations
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Aripiprazole monotherapy in the treatment of acute bipolar I mania: a randomized, double-blind, placebo- and lithium-controlled study.
Paul E. Keck,Paul J. Orsulak,Andrew J. Cutler,Raymond Sanchez,Anne Torbeyns,R. Marcus,Robert D. McQuade,William H. Carson +7 more
TL;DR: Aripiprazole provided statistically significant improvement of acute mania within 2 days, continuing over 3 weeks and sustained over 12 weeks; with lithium were nausea, headache, constipation, and tremor.
Journal ArticleDOI
Cognitive dysfunctions and white matter lesions in patients with bipolar disorder in remission.
Lydia Krabbendam,Adriaan Honig,J. Wiersma,Eric F. P. M. Vuurman,Paul A. M. Hofman,Mayke M. A. Derix,Willem A. Nolen,Jelle Jolles +7 more
TL;DR: Cognitive dysfunctions and white matter lesions in patients with bipolar disorder in remission are studied to find out why some patients remain in remission while others are not.
Journal ArticleDOI
Topiramate versus bupropion SR when added to mood stabilizer therapy for the depressive phase of bipolar disorder: a preliminary single-blind study.
Roger S. McIntyre,Deborah A Mancini,Sonia McCann,Janaki Srinivasan,Doron Sagman,Sidney H. Kennedy +5 more
TL;DR: Preliminary data suggest that adjunctive topiramate may reduce depressive symptom severity in acute bipolar depression and the antidepressant efficacy of this compound requires confirmation via double-blind placebo controlled investigation.
Journal ArticleDOI
Decreased levels of serum brain-derived neurotrophic factor in both depressed and euthymic patients with unipolar depression and in euthymic patients with bipolar I and II disorders.
TL;DR: Present results confirm previous independent findings of reduced circulating BDNF in patients with MDD and report, for the first time, decreased serum BDNF levels in euthymic patients with UD, BD-I and BD-II, independently from drug treatment status and concomitant Axis I psychiatric disorders.
Journal ArticleDOI
A prospective, longitudinal study of percentage of time spent ill in patients with bipolar I or bipolar II disorders.
TL;DR: Time spent in minor and subsyndromal mood states as well as with mania and depression in a cohort of well characterized bipolar I and II patients who were followed prospectively for an average of three years is examined.
References
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Book
Nonparametric statistics for the behavioral sciences
TL;DR: This is the revision of the classic text in the field, adding two new chapters and thoroughly updating all others as discussed by the authors, and the original structure is retained, and the book continues to serve as a combined text/reference.
Journal ArticleDOI
A rating scale for depression
TL;DR: The present scale has been devised for use only on patients already diagnosed as suffering from affective disorder of depressive type, used for quantifying the results of an interview, and its value depends entirely on the skill of the interviewer in eliciting the necessary information.
Journal ArticleDOI
The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Journal ArticleDOI
Diagnostic criteria for use in psychiatric research.
John P. Feighner,Eli Robins,Samuel B. Guze,Robert A. Woodruff,George Winokur,Rodrigo A. Munoz +5 more
TL;DR: Diagnostic criteria for 14 psychiatric illnesses along with the validating evidence for these diagnostic categories comes from workers outside the authors' group as well as from those within; it consists of studies of both outpatients and inpatients, of family studies, and of follow-up studies.