Journal ArticleDOI
A rating scale for mania: reliability, validity and sensitivity.
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The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently, and also correlated with the number of days of subsequent stay in hospital.Abstract:
An eleven item clinician-administered Mania Rating Scale (MRS) is introduced, and its reliability, validity and sensitivity are examined. There was a high correlation between the scores of two independent clinicians on both the total score (0.93) and the individual item scores (0.66 to 0.92). The MRS score correlated highly with an independent global rating, and with scores of two other mania rating scales administered concurrently. The score also correlated with the number of days of subsequent stay in hospital. It was able to differentiate statistically patients before and after two weeks of treatment and to distinguish levels of severity based on the global rating.read more
Citations
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The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. II. Baseline characteristics of the "prodromal" sample.
Tandy J. Miller,Robert B. Zipursky,Diana O. Perkins,Jean Addington,Scott W. Woods,Keith A. Hawkins,Ralph E. Hoffman,Adrian Preda,Irvin Epstein,D. Addington,Stacy R. Lindborg,E. Marquez,Mauricio Tohen,Alan Breier,Thomas H. McGlashan +14 more
TL;DR: The first double-blind placebo-controlled clinical trial of an atypical neuroleptic medication is being conducted in symptomatic treatment-seeking patients meeting new diagnostic criteria for a putative prodromal syndrome, identifying them as being at high risk for developing psychosis in the near future.
Journal ArticleDOI
Neurocognitive function in unaffected first-degree relatives of patients with bipolar disorder: a preliminary report
TL;DR: The selective deficits in executive control and declarative memory exhibited by relatives in this study have previously been reported in euthymic BD patients suggesting they may be useful endophenotypic markers of genetic vulnerability to BD.
Journal ArticleDOI
Neurocognitive profiles in bipolar I and bipolar II disorder: differences in pattern and magnitude of dysfunction
Carmen Simonsen,Kjetil Sundet,Anja Vaskinn,Astrid B. Birkenaes,John A. Engh,Charlotte Fredslund Hansen,Halldóra Jónsdóttir,Petter Andreas Ringen,Stein Opjordsmoen,Svein Friis,Ole A. Andreassen +10 more
TL;DR: Bipolar I patients have more widespread cognitive dysfunction both in pattern and magnitude, and a higher proportion has clinically significant cognitive impairments compared with patients with bipolar II, which may suggest neurobiological differences between the two bipolar subgroups.
Journal ArticleDOI
Sustained attention-deficit confirmed in euthymic bipolar disorder but not in first-degree relatives of bipolar patients or euthymic unipolar depression
TL;DR: A deficit of sustained attention is not present in patients with recurrent major depression tested during remission nor is it discriminable in the first-degree relatives of bipolar probands, suggesting that the confirmed abnormality in euthymic bipolar patients may be acquired as a consequence of bipolar illness.
Journal ArticleDOI
White matter abnormalities in children with and at risk for bipolar disorder
Jean A. Frazier,Janis L. Breeze,Janis L. Breeze,George Papadimitriou,David N. Kennedy,Steven M. Hodge,Constance M. Moore,James D. Howard,Michael P Rohan,Michael P Rohan,Verne S. Caviness,Nikos Makris +11 more
TL;DR: The finding of decreased FA in the right and left CG-PAC(WM) in children with BPD compared to the other two groups may represent a disease-state related finding.
References
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Book
Nonparametric statistics for the behavioral sciences
TL;DR: This is the revision of the classic text in the field, adding two new chapters and thoroughly updating all others as discussed by the authors, and the original structure is retained, and the book continues to serve as a combined text/reference.
Journal ArticleDOI
A rating scale for depression
TL;DR: The present scale has been devised for use only on patients already diagnosed as suffering from affective disorder of depressive type, used for quantifying the results of an interview, and its value depends entirely on the skill of the interviewer in eliciting the necessary information.
Journal ArticleDOI
The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
Journal ArticleDOI
Diagnostic criteria for use in psychiatric research.
John P. Feighner,Eli Robins,Samuel B. Guze,Robert A. Woodruff,George Winokur,Rodrigo A. Munoz +5 more
TL;DR: Diagnostic criteria for 14 psychiatric illnesses along with the validating evidence for these diagnostic categories comes from workers outside the authors' group as well as from those within; it consists of studies of both outpatients and inpatients, of family studies, and of follow-up studies.