Journal ArticleDOI
A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies.
TLDR
This review focuses on chemometric techniques and pharmaceutical NIRS applications, covering qualitative analyses, quantitative methods and on-line applications for near-infrared spectroscopy for pharmaceutical forms.About:
This article is published in Journal of Pharmaceutical and Biomedical Analysis.The article was published on 2007-07-27. It has received 1041 citations till now.read more
Citations
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Journal ArticleDOI
Structural changes of milk components during acid-induced coagulation kinetics as studied by synchronous fluorescence and mid-infrared spectroscopy.
TL;DR: Compared to rheometry, which reveals microstructure changes only in the gel state, spectroscopic methods make it possible to monitor molecular structure changes in micelles throughout the acidification processes.
Journal ArticleDOI
Scalable calibration transfer without standards via dynamic time warping for near-infrared spectroscopy
Congming Zou,Huimin Zhu,Shen Junru,He Yue,Su Jia'en,Xiaqiong Fan,Hongmei Lu,Zhimin Zhang,Yi Chen +8 more
TL;DR: A standard-free calibration transfer method has been developed for NIR spectroscopy based on variable penalty dynamic time warping and it is shown that this method can be applied to high-performance liquid chromatography systems.
Journal ArticleDOI
Discrimination of Radix Paeoniae varieties on the basis of their geographical origin by a novel method combining high-performance liquid chromatography and Fourier transform infrared spectroscopy measurements
TL;DR: In this article, a novel analytical method for complex samples, based on combined or fused high-performance liquid chromatography (HPLC) and Fourier transform infrared spectroscopy (FT-IR) data, was compared with that based on measurements from either of the techniques.
Journal ArticleDOI
Chemometrics and Experimental Design for the Quantification of Nitrate Salts in Nitric Acid: Near-Infrared Spectroscopy Absorption Analysis
TL;DR: In this article, real-time spectroscopic monitoring of radiochemical processing streams in hot cell environments requires efficiency and simplicity, and the success of optical spectroscopy for the hot cell environment is demonstrated.
Journal ArticleDOI
Moisture content determination in an antibody-drug conjugate freeze-dried medicine by near-infrared spectroscopy: A case study for release testing.
Matthieu Clavaud,Matthieu Clavaud,Yves Roggo,Klara Dégardin,Pierre-Yves Sacre,Philippe Hubert,Eric Ziemons +6 more
TL;DR: A validation strategy was introduced as a basis for submission to the health authorities' for release and stability activities in a cGMP environment in replacement to Karl Fischer (KF) method.
References
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Book
Neural Networks: A Comprehensive Foundation
TL;DR: Thorough, well-organized, and completely up to date, this book examines all the important aspects of this emerging technology, including the learning process, back-propagation learning, radial-basis function networks, self-organizing systems, modular networks, temporal processing and neurodynamics, and VLSI implementation of neural networks.
Journal ArticleDOI
Classification and Regression Trees.
Book
Classification and regression trees
TL;DR: The methodology used to construct tree structured rules is the focus of a monograph as mentioned in this paper, covering the use of trees as a data analysis method, and in a more mathematical framework, proving some of their fundamental properties.
Journal ArticleDOI
Nearest neighbor pattern classification
Thomas M. Cover,Peter E. Hart +1 more
TL;DR: The nearest neighbor decision rule assigns to an unclassified sample point the classification of the nearest of a set of previously classified points, so it may be said that half the classification information in an infinite sample set is contained in the nearest neighbor.