Journal ArticleDOI
A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies.
TLDR
This review focuses on chemometric techniques and pharmaceutical NIRS applications, covering qualitative analyses, quantitative methods and on-line applications for near-infrared spectroscopy for pharmaceutical forms.About:
This article is published in Journal of Pharmaceutical and Biomedical Analysis.The article was published on 2007-07-27. It has received 1041 citations till now.read more
Citations
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Journal ArticleDOI
Multiresolution interval partial least squares: A framework for waveband selection and resolution optimization
Tiago J. Rato,Marco S. Reis +1 more
TL;DR: A multiresolution selection algorithm that simultaneously selects the most relevant wavebands and their optimal resolution is here proposed and leads to prediction models that are at least as good as the full-spectrum models.
Journal ArticleDOI
Near-infrared spectroscopy for the quantitative determination of mass transfer and water absorption kinetics by a polymer solution
TL;DR: In this paper, a method to quantify the water absorption kinetics and the mass transfer in a polymer solution by using near-infrared (NIR) spectroscopy and partial least-squares (PLS) models, while it is exposed to a humid atmosphere is presented.
Journal ArticleDOI
Physical-chemical characterization and quality control of spironolactone raw material samples
F. C. Brandão,M. P. Tagiari,Marcos Antonio Segatto Silva,Lucas Freitas Berti,Hellen Karine Stulzer +4 more
TL;DR: In this paper, the quality of four spironolactone raw samples, derived from distinct laboratories, through thermal analysis (DSC and TG), infrared spectroscopy (IV), solubility assay, scanning electron microscopy, and digital image analysis, was established.
Journal ArticleDOI
Prediction of tablet characteristics based on sparse modeling for residual stresses simulated by the finite element method incorporating Drucker-Prager cap model
Kozo Takayama,Kozo Takayama,Tsubasa Sato,Kazuki Sato,Hiroaki Todo,Yasuko Obata,Kenji Sugibayashi +6 more
TL;DR: In this paper, the effects of residual stresses on the mechanical characteristics of tablets such as tensile strength (TS) and disintegration time (DT) were investigated using the finite element method (FEM), in which the powder compaction was represented by a Drucker-Prager cap model under unconstrained condition.
Journal ArticleDOI
The influence of different acquisition settings and the focus adjustment on Raman spectral maps of pharmaceutical tablets
TL;DR: In this article, the effect of levels of the spotlight, and other instrumental parameters for mapping industrially manufactured pharmaceutical tablets and to find out suitable, preferably robust, parameters for routine analyses is investigated.
References
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Book
Neural Networks: A Comprehensive Foundation
TL;DR: Thorough, well-organized, and completely up to date, this book examines all the important aspects of this emerging technology, including the learning process, back-propagation learning, radial-basis function networks, self-organizing systems, modular networks, temporal processing and neurodynamics, and VLSI implementation of neural networks.
Journal ArticleDOI
Classification and Regression Trees.
Book
Classification and regression trees
TL;DR: The methodology used to construct tree structured rules is the focus of a monograph as mentioned in this paper, covering the use of trees as a data analysis method, and in a more mathematical framework, proving some of their fundamental properties.
Journal ArticleDOI
Nearest neighbor pattern classification
Thomas M. Cover,Peter E. Hart +1 more
TL;DR: The nearest neighbor decision rule assigns to an unclassified sample point the classification of the nearest of a set of previously classified points, so it may be said that half the classification information in an infinite sample set is contained in the nearest neighbor.