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Journal ArticleDOI

A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies.

TLDR
This review focuses on chemometric techniques and pharmaceutical NIRS applications, covering qualitative analyses, quantitative methods and on-line applications for near-infrared spectroscopy for pharmaceutical forms.
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This article is published in Journal of Pharmaceutical and Biomedical Analysis.The article was published on 2007-07-27. It has received 1041 citations till now.

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Citations
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Journal ArticleDOI

Process analytical technologies and injectable drug products: Is there a future?

TL;DR: This review has the objective to provide a framework for the practical implementation of the QbD approach to injectable formulations, including application of diverse risk assessment and factorial design tools.
Journal ArticleDOI

Chemical Composition Monitoring in a Batch Distillation Process Using Raman Spectroscopy

TL;DR: In this paper, the authors used Raman spectroscopy to monitor the batch distillation of an ethanol/water mixture in a sieve-plate column and determined the chemical composition of the top product as a function of process time.
Journal ArticleDOI

Application of ATR-FTIR spectroscopy and chemometrics for the discrimination of furnace oil, gas oil and mazut oil

TL;DR: In this paper, principal component analysis (PCA), extended canonical variates analysis (ECVA), and interval Extended Extended Canonical Variates Analysis (iECVA) were used.
Journal ArticleDOI

Application of infrared portable sensor technology for predicting perceived astringency of acidic whey protein beverages

TL;DR: The portable infrared technique allowed rapid prediction of astringency of acidic whey protein beverages, providing the industry a novel tool for monitoring sensory characteristics of whey-containing beverages.
Journal ArticleDOI

Two-dimensional fluorescence as soft sensor in the monitoring of biotransformation performed by yeast.

TL;DR: This work applies soft sensor based on excitation‐emission fluorescence for the first time applied for the monitoring of biotransformation production of 2‐phenylethanol by yeast strains with high accuracy and precision.
References
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Book

Neural Networks: A Comprehensive Foundation

Simon Haykin
TL;DR: Thorough, well-organized, and completely up to date, this book examines all the important aspects of this emerging technology, including the learning process, back-propagation learning, radial-basis function networks, self-organizing systems, modular networks, temporal processing and neurodynamics, and VLSI implementation of neural networks.
Book

Classification and regression trees

Leo Breiman
TL;DR: The methodology used to construct tree structured rules is the focus of a monograph as mentioned in this paper, covering the use of trees as a data analysis method, and in a more mathematical framework, proving some of their fundamental properties.
Journal ArticleDOI

Nearest neighbor pattern classification

TL;DR: The nearest neighbor decision rule assigns to an unclassified sample point the classification of the nearest of a set of previously classified points, so it may be said that half the classification information in an infinite sample set is contained in the nearest neighbor.
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