Journal ArticleDOI
A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies.
TLDR
This review focuses on chemometric techniques and pharmaceutical NIRS applications, covering qualitative analyses, quantitative methods and on-line applications for near-infrared spectroscopy for pharmaceutical forms.About:
This article is published in Journal of Pharmaceutical and Biomedical Analysis.The article was published on 2007-07-27. It has received 1041 citations till now.read more
Citations
More filters
Journal ArticleDOI
Variables selection methods in near-infrared spectroscopy.
TL;DR: This review focuses on the variable selection methods in NIR spectroscopy with some classical approaches and sophisticated methods such as successive projections algorithm (SPA), uninformative variable elimination (UVE) and elaborate search-based strategies.
Journal ArticleDOI
Qualitative and quantitative analysis of lignocellulosic biomass using infrared techniques: A mini-review
TL;DR: In this article, the progress and applications of infrared techniques in biomass study, and compares the infrared and the wet chemical methods for composition analysis, are summarized and compared, in addition to reviewing recent studies of biomass structure and composition.
Journal ArticleDOI
Multivariate data analysis in pharmaceutics: a tutorial review.
Tarja Rajalahti,Olav M. Kvalheim +1 more
TL;DR: An overview of latent variable methods used in pharmaceutics and integrated with advanced characterization techniques such as vibrational spectroscopy is provided.
Journal ArticleDOI
Antioxidants: Characterization, natural sources, extraction and analysis
Mircea Oroian,Isabel Escriche +1 more
TL;DR: In this paper the main classes of antioxidants are presented: vitamins, carotenoids and polyphenols.
References
More filters
Journal ArticleDOI
A rapid quantitative assay of intact paracetamol tablets by reflectance near-infrared spectroscopy.
TL;DR: Near-infrared (NIR) reflectance spectroscopy was used to determine rapidly and non-destructively the content of paracetamol in bulk batches of intact Sterwin 500 mg tablets by collecting NIR spectra in the range 1100–2500 nm and using a multiple linear regression calibration method.
Journal ArticleDOI
Application of NIR reflectance spectroscopy for the identification of pharmaceutical excipients
TL;DR: In this article, the classification of powdered and microcristalline celluloses as well as cellulose and cellulose ethers is made possible by factor analysis and soft independent modelling of class analogies (SIMCA).
Journal ArticleDOI
Quantitative determination of crystallinity of alpha-lactose monohydrate by Near Infrared Spectroscopy (NIRS)
TL;DR: NIRS can be used for the quantitative determination of crystallinity of materials during pharmaceutical procedures and showed that NIRS is an useful method for accurately determining low quantities of the crystalline lactose in a physical mixture.
Journal ArticleDOI
Near-infrared determination of active substance content in intact low-dosage tablets
TL;DR: Diffuse reflectance NIR has the potential to become a reliable and robust quality control method for determining active tablet content and was conducted with two low-dosage pharmaceutical forms.
Journal ArticleDOI
Nondestructive near-infrared spectroscopic measurement of multiple analytes in undiluted samples of serum-based cell culture media.
TL;DR: NIR spectroscopy can be used effectively in the off‐line measurement of important nutrients (glucose and glutamine) and byproducts (lactate and ammonia) in a serum‐based animal cell culture medium.