Journal ArticleDOI
A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies.
TLDR
This review focuses on chemometric techniques and pharmaceutical NIRS applications, covering qualitative analyses, quantitative methods and on-line applications for near-infrared spectroscopy for pharmaceutical forms.About:
This article is published in Journal of Pharmaceutical and Biomedical Analysis.The article was published on 2007-07-27. It has received 1041 citations till now.read more
Citations
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Journal ArticleDOI
Implementation of Near-Infrared Spectroscopy for In-Line Monitoring of a Dehydration Reaction in a Tubular Laminar Reactor
Aleksandar Mitic,Albert E. Cervera-Padrell,Asmus R. Mortensen,Asmus R. Mortensen,Tommy Skovby,Kim Dam-Johansen,Irakli Javakhishvili,Søren Hvilsted,Krist V. Gernaey +8 more
TL;DR: In this paper, a simplified procedure for designing mesoscale tubular reactors is demonstrated together with performance outside of the normal operation windows (higher pressures and temperatures above normal boiling points of solvents). Noninvasive in-line real-time monitoring was established by using Fourier transform near-infrared (FT-NIR) spectrosco.
Journal ArticleDOI
The influence of residual water on the secondary structure and crystallinity of freeze-dried fibrinogen
TL;DR: The results demonstrated that the combined ATR-FTIR and Raman approach could be used to predict the crystalline state in freeze-dried fibrinogen products.
Journal ArticleDOI
Application of Near-infrared Spectroscopy and Multiple Spectral Algorithms to Explore the Effect of Soil Particle Sizes on Soil Nitrogen Detection
Shupei Xiao,Yong He +1 more
TL;DR: It was indicated that the larger the gap between soil particle sizes, the worse the accuracy of soil nitrogen detection, and it is of great significance to optimize the pre-treatments of soil samples to realize rapid and accurate detection by NIR spectroscopy.
Journal ArticleDOI
Classification of Ciprofloxacin Tablets Using Near-Infrared Spectroscopy and Chemometric Modeling.
TL;DR: A quadratic discriminant analysis (QDA) model was built following dimensionality reduction by principal component analysis for the purpose of predicting the origin of ciprofloxacin tablets and was able to correctly classify a collection of 907 tablets with greater than 96% accuracy.
Journal ArticleDOI
Effect of Sampling Frequency for Real-Time Tablet Coating Monitoring Using Near Infrared Spectroscopy.
TL;DR: How sampling practices affected the interpretation of the results provided by a near-infrared spectroscopy method for the monitoring of tablet moisture and coating weight gain during a pan-coating experiment is studied.
References
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Book
Neural Networks: A Comprehensive Foundation
TL;DR: Thorough, well-organized, and completely up to date, this book examines all the important aspects of this emerging technology, including the learning process, back-propagation learning, radial-basis function networks, self-organizing systems, modular networks, temporal processing and neurodynamics, and VLSI implementation of neural networks.
Journal ArticleDOI
Classification and Regression Trees.
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Classification and regression trees
TL;DR: The methodology used to construct tree structured rules is the focus of a monograph as mentioned in this paper, covering the use of trees as a data analysis method, and in a more mathematical framework, proving some of their fundamental properties.
Journal ArticleDOI
Nearest neighbor pattern classification
Thomas M. Cover,Peter E. Hart +1 more
TL;DR: The nearest neighbor decision rule assigns to an unclassified sample point the classification of the nearest of a set of previously classified points, so it may be said that half the classification information in an infinite sample set is contained in the nearest neighbor.