Journal ArticleDOI
A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies.
TLDR
This review focuses on chemometric techniques and pharmaceutical NIRS applications, covering qualitative analyses, quantitative methods and on-line applications for near-infrared spectroscopy for pharmaceutical forms.About:
This article is published in Journal of Pharmaceutical and Biomedical Analysis.The article was published on 2007-07-27. It has received 1041 citations till now.read more
Citations
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Journal ArticleDOI
Review of near-infrared spectroscopy as a process analytical technology for real-time product monitoring in dairy processing
TL;DR: This review focuses on the use of NIR technology for real-time monitoring of dairy products, by briefly outlining the measurement principle, NIR instrument configurations, in-line sampling methods, calibration models development, and current state of the art in on-line and in- line NIR applications for continuous process monitoring in the production of dairy Products.
Journal ArticleDOI
Rapid and nondestructive analysis of pharmaceutical products using near-infrared diffuse reflectance spectroscopy.
TL;DR: The results show that the spectra of the samples in the four forms can be measured with an acceptable repeatability, and classification of manufacture sites and quantitative analysis of the active pharmaceutical ingredient (API) can be achieved by principal component analysis (PCA) and partial least squares (PLS) regression, respectively.
Journal ArticleDOI
Cyber-physical-based PAT (CPbPAT) framework for Pharma 4.0.
TL;DR: This paper proposes a cyber-physical-based PAT framework called CPbPAT for implementing smart manufacturing systems in the pharmaceutical industry using an agent-based system and is presented by a standard system modeling language called the Unified Modeling Language (UML).
Journal ArticleDOI
Portable near-infrared instruments: Application for quality control of polymorphs in pharmaceutical raw materials and calibration transfer
TL;DR: The methods developed demonstrated a flexible, easy, cheap and fast way for quality control of MBZ polymorphs in incoming material, mainly in pharmaceutical laboratory chains.
Journal ArticleDOI
Digital imaging as a process analytical technology tool for fluid-bed pellet coating process.
TL;DR: Digital visual imaging as process analytical technology (PAT) tool for fluid-bed pellet coating processes according to PAT guidance is evaluated and results indicated that the method is feasible for real-time controlling, understanding, designing and optimizing of fluid- bed pellet coatings processes.
References
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Book
Neural Networks: A Comprehensive Foundation
TL;DR: Thorough, well-organized, and completely up to date, this book examines all the important aspects of this emerging technology, including the learning process, back-propagation learning, radial-basis function networks, self-organizing systems, modular networks, temporal processing and neurodynamics, and VLSI implementation of neural networks.
Journal ArticleDOI
Classification and Regression Trees.
Book
Classification and regression trees
TL;DR: The methodology used to construct tree structured rules is the focus of a monograph as mentioned in this paper, covering the use of trees as a data analysis method, and in a more mathematical framework, proving some of their fundamental properties.
Journal ArticleDOI
Nearest neighbor pattern classification
Thomas M. Cover,Peter E. Hart +1 more
TL;DR: The nearest neighbor decision rule assigns to an unclassified sample point the classification of the nearest of a set of previously classified points, so it may be said that half the classification information in an infinite sample set is contained in the nearest neighbor.