Journal ArticleDOI
A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies.
TLDR
This review focuses on chemometric techniques and pharmaceutical NIRS applications, covering qualitative analyses, quantitative methods and on-line applications for near-infrared spectroscopy for pharmaceutical forms.About:
This article is published in Journal of Pharmaceutical and Biomedical Analysis.The article was published on 2007-07-27. It has received 1041 citations till now.read more
Citations
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Journal ArticleDOI
Near-Infrared Spectroscopy to Determine Residual Moisture in Freeze-Dried Products: Model Generation by Statistical Design of Experiments.
Matthieu Clavaud,Matthieu Clavaud,Carmen Lema-Martinez,Yves Roggo,Michael Bigalke,Aurélie Guillemain,Philippe Hubert,Eric Ziemons,Andrea Allmendinger +8 more
TL;DR: The DoE-based model can be used to monitor MC during drug product development work including scale-up, and transfer without the need to update the NIR model if protein:sugar ratio and MC stays within the tested limits and cake structure remains macroscopically intact.
Journal ArticleDOI
Study of organo-hybrid layered double hydroxides by medium and near infrared spectroscopy.
TL;DR: An Mg/Al layered double hydroxide (LDH) containing carbonate ion in its interlayer region was examined by medium infrared (MIR) and near infrared reflectance spectroscopy (NIRS) and found to exhibit the overtone and combination bands for the hydroxyl groups in addition to those typical bands of the organic host functions.
Journal ArticleDOI
Composition analysis of falsified chloroquine phosphate samples seized during the COVID-19 pandemic.
C.A. Waffo Tchounga,Pierre-Yves Sacre,P.H. Ciza,R. Ngono,Eric Ziemons,Ph. Hubert,Roland Djang’eing’a Marini +6 more
TL;DR: This study involved eight chloroquine phosphate medicines seized in Cameroon, Democratic Republic of Congo and Niger during March and May 2020 and confirmed that four samples had been adulterated with paracetamol in trace amounts and two of them presented traces of chloramphenicol.
Journal ArticleDOI
A online NIR sensor for the pilot-scale extraction process in Fructus aurantii coupled with single and ensemble methods.
TL;DR: An ensemble method of online Nir sensor is proposed as a means of monitoring the pilot-scale extraction process in Fructus aurantii, which may also constitute a suitable strategy for online NIR monitoring of CHM.
Journal ArticleDOI
Calibration Transfer Based on Affine Invariance for NIR without Transfer Standards
TL;DR: A calibration transfer method based on affine invariance without transfer standards (CTAI) to adjust the difference between two instruments by affine transformation, which shows that CTAI is generally better than the others, and at least statistically the same.
References
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Book
Neural Networks: A Comprehensive Foundation
TL;DR: Thorough, well-organized, and completely up to date, this book examines all the important aspects of this emerging technology, including the learning process, back-propagation learning, radial-basis function networks, self-organizing systems, modular networks, temporal processing and neurodynamics, and VLSI implementation of neural networks.
Journal ArticleDOI
Classification and Regression Trees.
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Classification and regression trees
TL;DR: The methodology used to construct tree structured rules is the focus of a monograph as mentioned in this paper, covering the use of trees as a data analysis method, and in a more mathematical framework, proving some of their fundamental properties.
Journal ArticleDOI
Nearest neighbor pattern classification
Thomas M. Cover,Peter E. Hart +1 more
TL;DR: The nearest neighbor decision rule assigns to an unclassified sample point the classification of the nearest of a set of previously classified points, so it may be said that half the classification information in an infinite sample set is contained in the nearest neighbor.