Journal ArticleDOI
ACG Clinical Guideline: Management of Crohn’s Disease in Adults
Gary R. Lichtenstein,Edward V. Loftus,Kim L. Isaacs,Miguel Regueiro,Lauren B. Gerson,Bruce E. Sands +5 more
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TLDR
This guideline is intended to be flexible, not necessarily indicating the only acceptable approach, and should be distinguished from standards of care that are inflexible and rarely violated.About:
This article is published in The American Journal of Gastroenterology.The article was published on 2018-04-01. It has received 755 citations till now. The article focuses on the topics: Management of Crohn's disease & Disease.read more
Citations
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Journal ArticleDOI
Corticosteroids, But Not TNF Antagonists, Are Associated With Adverse COVID-19 Outcomes in Patients With Inflammatory Bowel Diseases: Results From an International Registry.
Erica J. Brenner,Ryan C. Ungaro,Richard B. Gearry,Gilaad G. Kaplan,Michele Kissous-Hunt,James D. Lewis,Siew C. Ng,Jean-François Rahier,Walter Reinisch,Frank M. Ruemmele,Flavio Steinwurz,Fox E. Underwood,Xian Zhang,Jean-Frederic Colombel,Michael D. Kappelman +14 more
TL;DR: Increasing age, comorbidities, and corticosteroids are associated with severe COVID-19 among IBD patients, although a causal relationship cannot be definitively established.
Journal ArticleDOI
ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment
Joana Torres,Stefanos Bonovas,Glen A. Doherty,Torsten Kucharzik,Javier P. Gisbert,Tim Raine,Michel Adamina,Michel Adamina,Alessandro Armuzzi,Oliver Bachmann,Palle Bager,Livia Biancone,Bernd Bokemeyer,Peter Bossuyt,Johan Burisch,Paul Collins,Alaa El-Hussuna,Pierre Ellul,Cornelia Frei-Lanter,Federica Furfaro,Christian Gingert,Paolo Gionchetti,Fernando Gomollón,Marien González-Lorenzo,Hannah Gordon,Tibor Hlavaty,Pascal Juillerat,Konstantinos H. Katsanos,Uri Kopylov,Eduards Krustins,Theodore Lytras,Christian Maaser,Fernando Magro,John Marshall,Pär Myrelid,Gianluca Pellino,Isadora Rosa,João Sabino,Edoardo Savarino,Antonino Spinelli,Laurents P. S. Stassen,Mathieu Uzzan,Stephan R. Vavricka,Bram Verstockt,Janindra Warusavitarne,Oded Zmora,Gionata Fiorino +46 more
TL;DR: The present article addresses surgical management, including preoperative aspects and drug management before surgery, and provides technical advice for a variety of common clinical situations.
Journal ArticleDOI
2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis.
Michael M. Ward,Atul Deodhar,Lianne S. Gensler,Maureen Dubreuil,David T. Y. Yu,Muhammad Asim Khan,Nigil Haroon,David G. Borenstein,Runsheng Wang,Ann Biehl,Meika A. Fang,Grant H. Louie,Vikas Majithia,Bernard Ng,Rosemary Bigham,Michael Pianin,Amit Aakash Shah,Nancy Sullivan,Marat Turgunbaev,Jeff Oristaglio,Amy S. Turner,Walter P. Maksymowych,Liron Caplan +22 more
TL;DR: To update evidence‐based recommendations for the treatment of patients with ankylosing spondylitis (AS) and nonradiographic axial spONDyloarthritis (SpA).
Journal ArticleDOI
Evidence-based clinical practice guidelines for inflammatory bowel disease
Katsuyoshi Matsuoka,Taku Kobayashi,Fumiaki Ueno,Toshiyuki Matsui,Fumihito Hirai,Nagamu Inoue,Jun Kato,Kenji Kobayashi,Kiyonori Kobayashi,Kazutaka Koganei,Reiko Kunisaki,Satoshi Motoya,Masakazu Nagahori,Hiroshi Nakase,Fumio Omata,Masayuki Saruta,Toshiaki Watanabe,Toshiaki Tanaka,Takanori Kanai,Yoshinori Noguchi,Ken Ichi Takahashi,Kenji Watanabe,Toshifumi Hibi,Yasuo Suzuki,Mamoru Watanabe,Kentaro Sugano,Tooru Shimosegawa +26 more
TL;DR: This English version was produced and edited based on the existing updated guidelines for ulcerative colitis and Crohn’s disease in Japanese, developed with the basic concept of the Grading of Recommendations Assessment, Development, and Evaluation system.
Journal ArticleDOI
The microbiome and inflammatory bowel disease.
TL;DR: The role of the gut microbiome in patients with IBD is discussed and the possible benefits of microbiome-modulating interventions, such as probiotics, prebiotics, antibiotics, fecal microbiota transplantation, and gene manipulation are discussed.
References
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Journal ArticleDOI
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Journal ArticleDOI
Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial
Stephen B. Hanauer,Brian G. Feagan,Gary R. Lichtenstein,Lloyd Mayer,Stefan Schreiber,Jean-Frederic Colombel,Daniel Rachmilewitz,Douglas C. Wolf,Allan Olson,Weihang Bao,Paul Rutgeerts +10 more
TL;DR: Patients with Crohn's disease who respond to an initial dose of infliximab are more likely to be in remission at weeks 30 and 54, to discontinue corticosteroids, and to maintain their response for a longer period of time, if inflIXimab treatment is maintained every 8 weeks.
Journal ArticleDOI
Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
Mark S. Silverberg,Jack Satsangi,Tariq Ahmad,Ian D. Arnott,Charles N. Bernstein,Steven R. Brant,Renzo Caprilli,Jean-Frederic Colombel,Christoph Gasche,Karel Geboes,Derek P. Jewell,Amir Karban,Edward V. Loftus,A. Salvador Peña,Robert H. Riddell,David B. Sachar,Stefan Schreiber,A. Hillary Steinhart,Stephan R. Targan,Severine Vermeire,Bryan F. Warren +20 more
TL;DR: The introduction of a widely acceptable clinical subclassification is strongly advocated, which would allow detailed correlations among serotype, genotype and clinical phenotype to be examined and confirmed in independent cohorts of patients and, thereby, provide a vital foundation for future work.
Journal ArticleDOI
Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease
Jean-Frederic Colombel,William J. Sandborn,Walter Reinisch,Gerassimos J. Mantzaris,Asher Kornbluth,Daniel Rachmilewitz,Simon Lichtiger,Robert H. Diamond,Delma L. Broussard,Kezhen L. Tang,C. Janneke van der Woude,Paul Rutgeerts +11 more
TL;DR: Patients with moderate-to-severe Crohn's disease who were treated with infliximab plus azathioprine or inflIXimab monotherapy were more likely to have a corticosteroid-free clinical remission than those receiving azATHioprine monotherapy.
Journal ArticleDOI
Infliximab for the treatment of fistulas in patients with Crohn's disease.
Daniel H. Present,Paul Rutgeerts,Stephan R. Targan,Stephen B. Hanauer,Lloyd Mayer,R. A. van Hogezand,Daniel K. Podolsky,Bruce E. Sands,T. Braakman,K. L. Dewoody,Th.F. Schaible,S. J. H. Van Deventer +11 more
TL;DR: Infliximab is an efficacious treatment for fistulas in patients with Crohn's disease and the most common adverse events for patients treated with infliximab were headache, abscess, upper respiratory tract infection, and fatigue.
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