Centromere Strength Provides the Cell Biological Basis for Meiotic Drive and Karyotype Evolution in Mice
Lukáš Chmátal,Sofia I. Gabriel,George P. Mitsainas,Jessica Martínez-Vargas,Jacint Ventura,Jeremy B. Searle,Richard M. Schultz,Michael A. Lampson +7 more
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TLDR
It is found that fusions preferentially segregate to the polar body in laboratory mouse strains when the fusion centromeres are weaker than those of telocentrics, which suggests that natural variation in centromere strength explains how the direction of drive can switch between populations.About:
This article is published in Current Biology.The article was published on 2014-10-06 and is currently open access. It has received 209 citations till now. The article focuses on the topics: Centromere & Meiotic drive.read more
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A Molecular View of Kinetochore Assembly and Function.
Andrea Musacchio,Arshad Desai +1 more
TL;DR: A broad summary of progress in the elucidation of the composition of the kinetochore and the identification of various physical and functional modules within its substructure has led to a much deeper molecular understanding of kinetchore organization and the origins of its functional output.
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The Ecology and Evolutionary Dynamics of Meiotic Drive
Anna K. Lindholm,Kelly A. Dyer,Renée C. Firman,Lila Fishman,Wolfgang Forstmeier,Luke Holman,Hanna Johannesson,Ulrich Knief,Hanna Kokko,Amanda M. Larracuente,Andri Manser,Catherine Montchamp-Moreau,Varos G. Petrosyan,Andrew Pomiankowski,Daven C. Presgraves,L. D. Safronova,Andreas Sutter,Robert L. Unckless,Rudi L. Verspoor,Nina Wedell,Gerald S. Wilkinson,Tom A. R. Price +21 more
TL;DR: Current knowledge of how natural drive systems function, how drivers spread through natural populations, and the factors that limit their invasion are reviewed.
Journal ArticleDOI
Variation in recombination frequency and distribution across eukaryotes: patterns and processes
Jessica Stapley,Philine G. D. Feulner,Philine G. D. Feulner,Susan E. Johnston,Anna W. Santure,Carole M. Smadja +5 more
TL;DR: The patterns of, and processes governing recombination in eukaryotes are explored, and how variation in rate and distribution relates to genome architecture, genetic and epigenetic mechanisms, sex, environmental perturbations and variable selective pressures is discussed.
Journal ArticleDOI
The origins of reproductive isolation in plants.
TL;DR: Important questions for the next decade include identifying the evolutionary forces responsible for chromosomal rearrangements, determining how often prezygotic barriers arise due to selection against hybrids, and establishing the relative importance of genomic conflicts in speciation.
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Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates
Christian S. Ottolini,Louise Newnham,Antonio Capalbo,Senthilkumar A. Natesan,Hrishikesh A. Joshi,Danilo Cimadomo,Darren K. Griffin,Karen Sage,Michael C. Summers,Alan R. Thornhill,Elizabeth A. Housworth,Alex Herbert,Laura Rienzi,Filippo Ubaldi,Alan H. Handyside,Eva Hoffmann +15 more
TL;DR: This work generates genome-wide maps of crossovers and chromosome segregation patterns by recovering all three products of single female meioses, and uncovers a new reverse chromosome segregation pattern in which both homologs separate their sister chromatids at meiosis I.
References
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Chromosomal rearrangements and speciation.
TL;DR: It is argued that rearrangements reduce gene flow more by suppressing recombination and extending the effects of linked isolation genes than by reducing fitness.
Journal ArticleDOI
The centromere paradox: stable inheritance with rapidly evolving DNA.
TL;DR: Incompatibilities between rapidly evolving Centromeric components may be responsible for both the organization of centromeric regions and the reproductive isolation of emerging species.
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Molecular architecture of the kinetochore–microtubule interface
Iain M. Cheeseman,Arshad Desai +1 more
TL;DR: The kinetochore is composed of a number of conserved protein complexes that direct its specification and assembly, bind to spindle microtubules and regulate chromosome segregation.
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Chromosomal speciation revisited: rearranging theory with pieces of evidence.
TL;DR: Re-examine theoretical predictions and revisit different sources of data to question some previous predictions and suggest new empirical and theoretical approaches to understanding the relevance of rearrangements in the origin of species.
Journal ArticleDOI
Female meiosis drives karyotypic evolution in mammals.
TL;DR: This evolutionary paradox is addressed by expanding the principle that nonrandom segregation of chromosomes takes place whenever human or mouse females are heterozygous carriers of Robertsonian translocations, a common form of chromosome rearrangement in mammals.
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