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ER-to-Golgi protein delivery through an interwoven, tubular network extending from ER.

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TLDR
In this article, a 3D view of early secretory compartments in mammalian cells with isotropic resolution and precise protein localization using whole-cell, focused ion beam scanning electron microscopy with cryo-structured illumination microscopy and live-cell synchronized cargo release approaches is provided.
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This article is published in Cell.The article was published on 2021-04-29. It has received 100 citations till now. The article focuses on the topics: COPI & COPII.

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Molecular mechanisms of endomembrane trafficking in plants.

TL;DR: In this paper, the authors summarize the current statet of knowledge on plant endomembrane trafficking, with a focus on four distinct trafficking pathways: ER-to-Golgi transport, endocytosis, trans-golgi network-tovacuole transport, and autophagy.
Journal ArticleDOI

Intertwined and Finely Balanced: Endoplasmic Reticulum Morphology, Dynamics, Function, and Diseases.

TL;DR: The endoplasmic reticulum (ER) is an organelle that is responsible for many essential subcellular processes as discussed by the authors, and it is becoming apparent that the complex morphology and dynamics of the ER are linked to its function.
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A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis.

TL;DR: The ERGIC-ERES contact is established by the interaction between TMED9 and SEC12 which generates a short distance opposition (as close as 2-5nm) between the two compartments.
References
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Journal ArticleDOI

Distinctive Image Features from Scale-Invariant Keypoints

TL;DR: This paper presents a method for extracting distinctive invariant features from images that can be used to perform reliable matching between different views of an object or scene and can robustly identify objects among clutter and occlusion while achieving near real-time performance.
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Lipid Rafts As a Membrane-Organizing Principle

TL;DR: The evidence for how this principle combines the potential for sphingolipid-cholesterol self-assembly with protein specificity to selectively focus membrane bioactivity is reviewed.
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Brefeldin A: insights into the control of membrane traffic and organelle structure.

TL;DR: The relationship between the control of membrane traffic and the maintenance of organelle structure has been investigated with the use of a remarkable drug, brefeldin A (BFA), and some speculative models concerning the mechanism and regulation ofmembrane traffic within the central vacuolar system are proposed.
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Model systems, lipid rafts, and cell membranes.

TL;DR: This review critically analyzes what is known of phase behavior and liquid-liquid immiscibility in model systems and compares these data with what isknown of domain formation in cell membranes.
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Three-Dimensional Resolution Doubling in Wide-Field Fluorescence Microscopy by Structured Illumination

TL;DR: This work describes how spatially structured illumination microscopy can be applied in three dimensions to double the axial as well as the lateral resolution, with true optical sectioning, and has produced the first light microscopy images of the synaptonemal complex in which the lateral elements are clearly resolved.
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