Human infection with avian influenza A H6N1 virus: an epidemiological analysis
Sung-Hsi Wei,Ji-Rong Yang,Ho-Sheng Wu,Ming-Chuan Chang,Jen-Shiou Lin,Chi-Yung Lin,Yu-Lun Liu,Yi-Chun Lo,Chin-Hui Yang,Jen-Hsiang Chuang,Min-Cheng Lin,Wen-Chen Chung,Chia-Hung Liao,Min-Shiuh Lee,Wan-Ting Huang,Pei-Jung Chen,Ming-Tsan Liu,Feng-Yee Chang +17 more
TLDR
This is the first report of human infection with a wild avian influenza A H6N1 virus and highlights the continuous need for preparedness for a pandemic of unpredictable and complexAvian influenza.About:
This article is published in The Lancet Respiratory Medicine.The article was published on 2013-12-01 and is currently open access. It has received 181 citations till now. The article focuses on the topics: Influenza A virus & Influenza A virus subtype H5N1.read more
Citations
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Advances in the development of influenza virus vaccines.
Florian Krammer,Peter Palese +1 more
TL;DR: Improvements have been made recently to enhance immune protection induced by seasonal and pandemic vaccines, and to speed up production in case of a pandemic.
Journal ArticleDOI
Genesis, Evolution and Prevalence of H5N6 Avian Influenza Viruses in China
Yuhai Bi,Quanjiao Chen,Qianli Wang,Jianjun Chen,Tao Jin,Gary Wong,Chuansong Quan,Jun Liu,Jun Wu,Renfu Yin,Lihua Zhao,Mingxin Li,Zhuang Ding,Rongrong Zou,Wen Xu,Hong Li,Huijun Wang,Kegong Tian,Guanghua Fu,Yu Huang,Alexander Shestopalov,Shoujun Li,Bing Xu,Hongjie Yu,Tingrong Luo,Lin Lu,Xun Xu,Yang Luo,Yingxia Liu,Weifeng Shi,Di Liu,George F. Gao +31 more
TL;DR: Phylogenetic analysis reveals that H5N6 arose from reassortments of H5 and H6N6 viruses, with the hemagglutinin and neuraminidase combinations being strongly lineage specific.
Journal ArticleDOI
Zoonotic Potential of Influenza A Viruses: A Comprehensive Overview.
TL;DR: An introduction on IAVs is provided, highlighting the mechanisms of viral evolution, the host spectrum, and the animal/human interface, and various approaches for the prevention of human IAV infections are provided.
Journal ArticleDOI
A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus
Ying Wu,Myung-Sam Cho,David A. Shore,Manki Song,Jung-ah Choi,Tao Jiang,Yong-Qiang Deng,Melissa Bourgeois,Lynn M Almli,Hua Yang,Li-Mei Chen,Yi Shi,Jianxu Qi,An Li,Kye Sook Yi,MinSeok Chang,Jin Soo Bae,Hyunjoo Lee,Ji-Young Shin,James Stevens,SeoungSuh Hong,Cheng-Feng Qin,George F. Gao,Shin Jae Chang,Ruben O. Donis +24 more
TL;DR: The antibody, designated CT149, was isolated from convalescent patients infected with pandemic H1N1 in 2009 and is found to neutralize all tested group 2 and some group 1 influenza A viruses by inhibiting low pH-induced, HA-mediated membrane fusion.
Journal ArticleDOI
Influenza at the animal-human interface: a review of the literature for virological evidence of human infection with swine or avian influenza viruses other than A(H5N1).
Gudrun S. Freidl,Adam Meijer,E. de Bruin,M De Nardi,Olga Munoz,Ilaria Capua,Andrew C. Breed,Kate Harris,A. Hill,R. Kosmider,Jill Banks,S Von Dobschuetz,S Von Dobschuetz,Katharina D.C. Stärk,Barbara Wieland,Kim B. Stevens,S van der Werf,Vincent Enouf,K. van der Meulen,K. Van Reeth,Gwenaelle Dauphin,Marion Koopmans +21 more
TL;DR: A review of the literature for evidence of human infection with animal influenza viruses by diagnostic methods used found reports of 1,419 naturally infected human cases, of which 648 were associated with avian influenza virus (AIV) A(H5N1), 375 with other AIV subtypes, and 396 with swine influenzairus (SIV).
References
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MEGA5: Molecular Evolutionary Genetics Analysis using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods
Koichiro Tamura,Daniel S. Peterson,Nicholas Peterson,Glen Stecher,Masatoshi Nei,Sudhir Kumar +5 more
TL;DR: The newest addition in MEGA5 is a collection of maximum likelihood (ML) analyses for inferring evolutionary trees, selecting best-fit substitution models, inferring ancestral states and sequences, and estimating evolutionary rates site-by-site.
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Universal primer set for the full-length amplification of all influenza A viruses.
TL;DR: The resultant primer set is suitable for all influenza A viruses to generate full-length cDNAs, to subtype viruses, to sequence their DNA, and to construct expression plasmids for reverse genetics systems.
Journal ArticleDOI
Structure and Receptor Specificity of the Hemagglutinin from an H5N1 Influenza Virus
James Stevens,Ola Blixt,Terrence M. Tumpey,Jeffery K. Taubenberger,James C. Paulson,Ian A. Wilson +5 more
TL;DR: The hemagglutinin structure at 2.9 angstrom resolution, from a highly pathogenic Vietnamese H5N1 influenza virus, is more related to the 1918 and other human H1 HAs than to a 1997 duck H5 HA, which suggests a path for this H 5N1 virus to gain a foothold in the human population.
Journal ArticleDOI
The influenza virus resource at the National Center for Biotechnology Information.
Yiming Bao,Pavel Bolotov,Dmitry Dernovoy,Boris Kiryutin,Leonid Zaslavsky,Tatiana Tatusova,Jim Ostell,David J. Lipman +7 more
TL;DR: The Influenza Genome Sequencing Project aims to rapidly sequence influenza viruses from samples collected all over the world, and in just over 2 years after the initiation of the project, more than 2,000 complete genomes of influenza viruses A and B had been deposited in GenBank.
GUEST COMMENTARY The Influenza Virus Resource at the National Center for Biotechnology Information
Yiming Bao,Pavel Bolotov,Dmitry Dernovoy,Boris Kiryutin,Leonid Zaslavsky,Tatiana Tatusova,Jim Ostell,David J. Lipman +7 more
TL;DR: The NCBI Influenza Virus Sequence Database (FLU) as mentioned in this paper was created at the National Institute of Allergy and Infectious Diseases (NIAID) to provide free access to viral sequences in a timely fashion.
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