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Likelihood-mapping: A simple method to visualize phylogenetic content of a sequence alignment

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TLDR
A graphical method, likelihood-mapping, is introduced, to visualize the phylogenetic content of a set of aligned sequences, based on an analysis of the maximum likelihoods for the three fully resolved tree topologies that can be computed for four sequences.
Abstract
We introduce a graphical method, likelihood-mapping, to visualize the phylogenetic content of a set of aligned sequences. The method is based on an analysis of the maximum likelihoods for the three fully resolved tree topologies that can be computed for four sequences. The three likelihoods are represented as one point inside an equilateral triangle. The triangle is partitioned in different regions. One region represents star-like evolution, three regions represent a well-resolved phylogeny, and three regions reflect the situation where it is difficult to distinguish between two of the three trees. The location of the likelihoods in the triangle defines the mode of sequence evolution. If n sequences are analyzed, then the likelihoods for each subset of four sequences are mapped onto the triangle. The resulting distribution of points shows whether the data are suitable for a phylogenetic reconstruction or not.

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Citations
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TREE-PUZZLE: maximum likelihood phylogenetic analysis using quartets and parallel computing.

TL;DR: TREE-PUZZLE is a program package for quartet-based maximum-likelihood phylogenetic analysis that provides methods for reconstruction, comparison, and testing of trees and models on DNA as well as protein sequences to reduce waiting time for larger datasets.
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Ultrafast Approximation for Phylogenetic Bootstrap

TL;DR: This work proposes an ultrafast bootstrap approximation approach (UFBoot) to compute the support of phylogenetic groups in maximum likelihood (ML) based trees and offers an efficient and easy-to-use software to perform the UFBoot analysis with ML tree inference.
Journal ArticleDOI

Phylogenomics resolves the timing and pattern of insect evolution

Bernhard Misof, +105 more
- 07 Nov 2014 - 
TL;DR: The phylogeny of all major insect lineages reveals how and when insects diversified and provides a comprehensive reliable scaffold for future comparative analyses of evolutionary innovations among insects.
Journal ArticleDOI

Sex and virulence in Escherichia coli: an evolutionary perspective

TL;DR: The evolution of virulence is linked to bacterial sex because rates of evolution have accelerated in pathogenic lineages, culminating in highly virulent organisms whose genomic contents are altered frequently by increased rates of homologous recombination.
References
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Journal ArticleDOI

Quartet Puzzling: A Quartet Maximum-Likelihood Method for Reconstructing Tree Topologies

TL;DR: A versatile method, quartet puzzling, is introduced to reconstruct the topology (branching pattern) of a phylogenetic tree based on DNA or amino acid sequence data and outperforms neighbor joining in some cases with high transition/transversion bias.
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African populations and the evolution of human mitochondrial DNA

TL;DR: The African origin hypothesis of human mtDNA evolution is supported by two statistical tests and two hypervariable segments of mtDNA were sequenced from 189 people of diverse geographic origin, including 121 native Africans.
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Estimation of evolutionary distances between nucleotide sequences

TL;DR: A formal mathematical analysis of the substitution process in nucleotide sequence evolution was done in terms of the Markov process by using matrix algebra theory, and it was shown that the multiparameter methods of Lanave et al.'s (J. Mol. Evol. 2:191–210, 1987) and Lanave and Hartigan's (Stat. Sci. Sci.) methods are preferable to others for the purpose of phylogenetic analysis when the sequences are long.
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A canonical decomposition theory for metrics on a finite set

TL;DR: In this article, the authors consider specific additive decompositions d = d 1 + … + d n of metrics, defined on a finite set X (where a metric may give distance zero to pairs of distinct points).
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Ribosomal DNA phylogeny of the major extant arthropod classes and the evolution of myriapods

TL;DR: Using nuclear ribosomal gene sequences for constructing a molecular phylogeny, this work provides strong evidence that the crustaceans and not the myriapods should be considered to be the sister group of the insects.
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