Neural Networks of the Mouse Neocortex
Brian Zingg,Houri Hintiryan,Lin Gou,Monica Y. Song,Maxwell Bay,Michael S. Bienkowski,Nicholas N. Foster,Seita Yamashita,Ian Bowman,Arthur W. Toga,Hong-Wei Dong +10 more
TLDR
Cortico-cortical connectivity map and connectivity matrices revealed that the entire cortex is organized into four somatic sensorimotor, two medial, and two lateral subnetworks that display unique topologies and can interact through select cortical areas.About:
This article is published in Cell.The article was published on 2014-02-27 and is currently open access. It has received 630 citations till now. The article focuses on the topics: Cortical map & Neocortex.read more
Citations
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An anterograde neuroanatomical tracing method that shows the detailed morphology of neurons, their axons and terminals: Immunohistochemical localization of an axonally transported plant lectin, Phaseolus vulgaris-leucoagglutinin (PHA-L).
TL;DR: A new neuroanatomical method for tracing connections in the central nervous system based on the anterograde axonal transport of the kidney bean lectin, Phaseolus vulgaris-leucoagglutinin (PHA-L) is described, which offers several advantages over present techniques.
Journal ArticleDOI
The neocortical circuit: themes and variations
TL;DR: Similarities in neocortical circuit organization across areas and species suggest a common strategy to process diverse types of information, including sensation from diverse modalities, motor control and higher cognitive processes.
Journal ArticleDOI
Networks of the Brain
TL;DR: Models of Network Growth All networks, whether they are social, technological, or biological, are the result of a growth process, and many continue to grow for prolonged periods of time, continually modifying their connectivity structure throughout their entire existence.
Journal ArticleDOI
Advancing the understanding of autism disease mechanisms through genetics
TL;DR: Current understanding of the genetic architecture of ASD is reviewed and genetic evidence, neuropathology and studies in model systems with how they inform mechanistic models of ASD pathophysiology are integrated.
Journal ArticleDOI
Mapping of Brain Activity by Automated Volume Analysis of Immediate Early Genes
Nicolas Renier,Eliza L. Adams,Christoph Kirst,Zhuhao Wu,Ricardo Azevedo,Johannes Kohl,Anita E. Autry,Lolahon R. Kadiri,Kannan Umadevi Venkataraju,Yu Zhou,Victoria X. Wang,Cheuk Y. Tang,Olav Olsen,Catherine Dulac,Pavel Osten,Marc Tessier-Lavigne +15 more
TL;DR: A pipeline for high-speed acquisition of brain activity at cellular resolution through profiling immediate early gene expression using immunostaining and light-sheet fluorescence imaging, followed by automated mapping and analysis of activity by an open-source software program that is widely applicable to different experimental paradigms, including animal species for which transgenic activity reporters are not readily available.
References
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Distributed Hierarchical Processing in the Primate Cerebral Cortex
TL;DR: A summary of the layout of cortical areas associated with vision and with other modalities, a computerized database for storing and representing large amounts of information on connectivity patterns, and the application of these data to the analysis of hierarchical organization of the cerebral cortex are reported on.
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The structure of the nervous system of the nematode Caenorhabditis elegans
TL;DR: The structure and connectivity of the nervous system of the nematode Caenorhabditis elegans has been deduced from reconstructions of electron micrographs of serial sections as discussed by the authors.
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How do you feel--now? The anterior insula and human awareness.
TL;DR: New findings suggest a fundamental role for the AIC (and the von Economo neurons it contains) in awareness, and thus it needs to be considered as a potential neural correlate of consciousness.
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The Human Connectome: A Structural Description of the Human Brain
TL;DR: A research strategy to achieve the connection matrix of the human brain (the human “connectome”) is proposed, and its potential impact is discussed.
Journal ArticleDOI
Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures
TL;DR: Behavior, anatomical, and gene expression studies that together support a functional segmentation into three hippocampal compartments are reviewed, finding gene expression in the dorsal hippocampus correlates with cortical regions involved in information processing, while genes expressed in the ventral hippocampus correlate with regions involved with emotion and stress.
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