Journal ArticleDOI
Physiological Pathways Regulating the Activity of Magnocellular Neurosecretory Cells
TLDR
This review considers the rôle played by particular afferent pathways in the regulation of the activity of oxytocin and vasopressin cells.About:
This article is published in Progress in Neurobiology.The article was published on 1999-04-01. It has received 307 citations till now. The article focuses on the topics: Vasopressin & Oxytocin.read more
Citations
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Journal ArticleDOI
The Oxytocin Receptor System: Structure, Function, and Regulation
Gerald Gimpl,Falk Fahrenholz +1 more
TL;DR: The regulation by gonadal and adrenal steroids is one of the most remarkable features of the OT system and is, unfortunately, the least understood.
Journal ArticleDOI
Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communication
Rainer Landgraf,Inga D. Neumann +1 more
TL;DR: This concept considers neuropeptides in the extracellular fluid of the brain rather than those in the cerebrospinal fluid or plasma as primary signals, triggering a variety of receptor-mediated effects, including those underlying behavioral and neuroendocrine regulation and psychopathology.
Journal ArticleDOI
Dendritic peptide release and peptide-dependent behaviours
Mike Ludwig,Gareth Leng +1 more
TL;DR: The recently demonstrated ability of neuropeptides to prime vesicle stores for activity-dependent release could lead to a temporary functional reorganization of neuronal networks harbouring specific peptide receptors, providing a substrate for long-lasting effects.
Journal ArticleDOI
Physiology of Vasopressin Relevant to Management of Septic Shock
TL;DR: Clinical use of vasopressin should await a randomized controlled trial of its effects on clinical outcomes such as organ failure and mortality, because clinical studies have been relatively small, focused on physiologic end points, and because of potential adverse effects of vasipressin.
Journal ArticleDOI
The hypothalamic-neurohypophysial system regulates the hypothalamic-pituitary-adrenal axis under stress: an old concept revisited.
TL;DR: Data supporting the concept of HNS effects on HPA axis activity is presented and their possible impact on some aspects of behavioural regulation and psychopathology is outlined.
References
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Journal ArticleDOI
Dendrites of hypothalamic magnocellular neurons release neurohypophysial peptides by exocytosis.
David V. Pow,John F. Morris +1 more
TL;DR: Morphometric analysis of stimulated slices demonstrates that exocytosis of neurosecretory granules from the dendrites of magnocellular neurons can account for the vasopressin and oxytocin known to be released into the hypothalamus.
Journal ArticleDOI
Emerging concepts of structure-function dynamics in adult brain: the hypothalamo-neurohypophysial system.
TL;DR: Progress in developing an ever more complete structural and functional picture of this system has been closely tied to advancements in technology, specifically in the areas of radioimmunoassay, immunocytochemistry, anatomical tracing methods at the light and electron microscopic levels, and sophisticated preparations for electrophysiological investigation.
Journal ArticleDOI
Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry
Lucy Vulchanova,Ulf Arvidsson,Maureen S. Riedl,Jian-Jun Wang,G. Buell,Annmarie Surprenant,R. A. North,Robert Elde +7 more
TL;DR: The location of the P2X1 subunit in smooth muscle is consistent with its role as a postjunctional receptor in autonomic transmission, while in neurons, these receptors appear in both postsynaptic and presynaptic locations.
Journal ArticleDOI
Noise-enhanced information transmission in rat SA1 cutaneous mechanoreceptors via aperiodic stochastic resonance.
TL;DR: Noise can serve to enhance the response of a sensory neuron to a perithreshold aperiodic input signal, suggesting a possible functional role for input noise in sensory systems and indicating that it may be possible to introduce noise artificially into sensory neurons to improve their abilities to detect arbitrary weak signals.
Journal ArticleDOI
Noise-induced enhancement of signal transduction across voltage-dependent ion channels
TL;DR: A hundred-fold increase in signal transduction induced by external noise is accompanied by a growth in the output signal-to-noise ratio, and the system of ion channels considered here represents the simplest biological system yet known to exhibit stochastic resonance.
Related Papers (5)
Dendrites of hypothalamic magnocellular neurons release neurohypophysial peptides by exocytosis.
David V. Pow,John F. Morris +1 more