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Journal ArticleDOI

Physiological Pathways Regulating the Activity of Magnocellular Neurosecretory Cells

Gareth Leng, +2 more
- 01 Apr 1999 - 
- Vol. 57, Iss: 6, pp 625-655
TLDR
This review considers the rôle played by particular afferent pathways in the regulation of the activity of oxytocin and vasopressin cells.
About
This article is published in Progress in Neurobiology.The article was published on 1999-04-01. It has received 307 citations till now. The article focuses on the topics: Vasopressin & Oxytocin.

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Citations
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Journal ArticleDOI

Differential GABAA receptor clustering determines GABA synapse plasticity in rat oxytocin neurons around parturition and the onset of lactation

TL;DR: The functional synaptic diversity at the postsynaptic level in dorsomedial SON neurons is correlated with a differential clustering of distinct GABA(A)R subtypes at individual synapses.
Journal ArticleDOI

Sex‐Dependent Effects of Prenatal Stress on Social Memory in Rats: A Role for Differential Expression of Central Vasopressin‐1a Receptors

TL;DR: The data support a role for altered signalling via central Avpr1a in PNS‐induced sex‐dependent changes in social memory and may have implications for understanding the aetiology of neurodevelopmental disorders characterised by social behaviour deficits in humans.
Journal ArticleDOI

Response of substances co-expressed in hypothalamic magnocellular neurons to osmotic challenges in normal and Brattleboro rats.

TL;DR: The intention of this review is to emphasize the current knowledge about the extent and importance of the substances co-localized with magnocellular arginine vasopressin (AVP) and oxytocin (OXY) as potential candidates for the gradual clarification of their actual role in the regulation of hydromineral homeostasis.
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Differential effects of vasopressin and norepinephrine on vascular reactivity in a long-term rodent model of sepsis.

TL;DR: This long-term animal model demonstrates changes in circulating vasoactive hormones similar to prolonged human sepsis, and decreased pressor sensitivity to norepinephrine.
Journal ArticleDOI

Vasopressin: A Review of Therapeutic Applications

TL;DR: The discovery of disease states involving VP and/or its receptors has offered the most insight into VP’s in vivo role and functional repertoire, and an appraisal of these conditions will be used to review current knowledge and clinical applications of VP and its synthetic agonists and antagonists.
References
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Journal ArticleDOI

Expression of c-fos protein in brain: metabolic mapping at the cellular level

TL;DR: Fos immunohistochemistry provides a cellular method to label polysynaptically activated neurons and thereby map functional pathways in response to polysynaptic activation.
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A potent and selective endogenous agonist for the mu-opiate receptor.

TL;DR: The discovery and isolation from brain of a peptide, endomorphin-1 (Tyr-Pro-Trp-Phe-NH2), which has the highest specificity and affinity for the µ receptor of any endogenous substance so far described and they maybe natural ligands for this receptor.
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The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat

TL;DR: The autoradiographic material, and additional double-labeling experiments, were used to identify and to characterize projections that interconnect the A1, A2 and A6 regions, as well as possible projections from these cell groups to the spinal cord.
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The anatomy of neuropeptide-Y-containing neurons in rat brain.

TL;DR: The extremely high concentrations and widespread distribution of neuropeptide Y in the central nervous system suggests a number of important physiological roles for this neurotransmitter candidate.
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Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the rat.

TL;DR: The findings indicate that central catecholamine neurons can be subdivided into distinct sub-groups based upon the coexistence of a specific peptide.
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