Journal ArticleDOI
Physiological Pathways Regulating the Activity of Magnocellular Neurosecretory Cells
TLDR
This review considers the rôle played by particular afferent pathways in the regulation of the activity of oxytocin and vasopressin cells.About:
This article is published in Progress in Neurobiology.The article was published on 1999-04-01. It has received 307 citations till now. The article focuses on the topics: Vasopressin & Oxytocin.read more
Citations
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Journal ArticleDOI
The Oxytocin Receptor System: Structure, Function, and Regulation
Gerald Gimpl,Falk Fahrenholz +1 more
TL;DR: The regulation by gonadal and adrenal steroids is one of the most remarkable features of the OT system and is, unfortunately, the least understood.
Journal ArticleDOI
Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communication
Rainer Landgraf,Inga D. Neumann +1 more
TL;DR: This concept considers neuropeptides in the extracellular fluid of the brain rather than those in the cerebrospinal fluid or plasma as primary signals, triggering a variety of receptor-mediated effects, including those underlying behavioral and neuroendocrine regulation and psychopathology.
Journal ArticleDOI
Dendritic peptide release and peptide-dependent behaviours
Mike Ludwig,Gareth Leng +1 more
TL;DR: The recently demonstrated ability of neuropeptides to prime vesicle stores for activity-dependent release could lead to a temporary functional reorganization of neuronal networks harbouring specific peptide receptors, providing a substrate for long-lasting effects.
Journal ArticleDOI
Physiology of Vasopressin Relevant to Management of Septic Shock
TL;DR: Clinical use of vasopressin should await a randomized controlled trial of its effects on clinical outcomes such as organ failure and mortality, because clinical studies have been relatively small, focused on physiologic end points, and because of potential adverse effects of vasipressin.
Journal ArticleDOI
The hypothalamic-neurohypophysial system regulates the hypothalamic-pituitary-adrenal axis under stress: an old concept revisited.
TL;DR: Data supporting the concept of HNS effects on HPA axis activity is presented and their possible impact on some aspects of behavioural regulation and psychopathology is outlined.
References
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Journal ArticleDOI
Influence of low- and high-pressure baroreflexes on vasopressin release in humans.
TL;DR: It is suggested that high-pressure baroreflexes (probably in concert with other mechanisms) during these circumstances play a more important role and that changes in arterial pulse pressure and in the PP profile over time may be more essential than changes in mean arterial pressure in regard to modulation of AVP release in humans.
Journal ArticleDOI
Neurophysiology of body fluid homeostasis.
TL;DR: There is evidence that, in the rat, oxytocin is a natriuretic hormone and the nature and identity of the osmoreceptors subserving oxytocIn and vasopressin release are discussed.
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Collateral input to the paraventricular and supraoptic nuclei in rat. II. Afferents from the ventral lateral medulla and nucleus tractus solitarius.
Mark L. Weiss,Glenn I. Hatton +1 more
TL;DR: Afferent inputs, in conjunction with the known inter- and intracellular changes that take place within the magnocellular nuclei, may be involved with the coordinated responses throughout magno cellular neuroendocrine system during medullary reflexes, i.e., the baroreceptor-mediated reflexes or the gastric distention reflexes.
Journal ArticleDOI
Chemoreceptor and baroreceptor responses of A1 area neurons projecting to supraoptic nucleus.
TL;DR: Electrophysiological evidence is provided that neurons projecting from the A1 area to the supraoptic nucleus increase their discharge rate in response to baroreceptor unloading and decrease their discharged rate inresponse to barOREceptor activation.
Journal ArticleDOI
Solitary nucleus excitation of supraoptic vasopressin cells via adrenergic afferents
Trevor A. Day,John R. Sibbald +1 more
TL;DR: In this paper, the authors examined the effect of medial NTS stimulation on antidromically identified SON neurosecretory cells that were classified as arginine vasopressin (AVP) or oxytocin (OXY) secreting in accord with basal activity patterns and responsiveness to arterial baroreceptor activation.
Related Papers (5)
Dendrites of hypothalamic magnocellular neurons release neurohypophysial peptides by exocytosis.
David V. Pow,John F. Morris +1 more