Journal ArticleDOI
Physiological Pathways Regulating the Activity of Magnocellular Neurosecretory Cells
TLDR
This review considers the rôle played by particular afferent pathways in the regulation of the activity of oxytocin and vasopressin cells.About:
This article is published in Progress in Neurobiology.The article was published on 1999-04-01. It has received 307 citations till now. The article focuses on the topics: Vasopressin & Oxytocin.read more
Citations
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Journal ArticleDOI
Integration of sodium and osmosensory signals in vasopressin neurons.
TL;DR: In rat vasopressin-containing neurons, local osmosensitivity is conferred by intrinsic stretch-inactivated cation channels and by taurine release from surrounding glia, providing a first glimpse of the integrative processes at work in a central osmoregulatory reflex.
Journal ArticleDOI
Diversity of oxytocin neurons: beyond magno- and parvocellular cell types?
TL;DR: A hypothesis suggesting that the central OT system is composed of more than just two OT cell types is proposed, which needs to be confirmed by the application of available genetic and anatomical techniques.
Journal ArticleDOI
Transgenesis and the Study of Expression, Cellular Targeting and Function of Oxytocin, Vasopressin and Their Receptors
rd W. Scott Young,Harold Gainer +1 more
TL;DR: The role of transgenics in deciphering gene elements necessary for the appropriate expression of oxytocin and vasopressin and to deliver exogenous genes, such as green fluorescent protein, selectively to secretory granules in the neurons in the hypothalamoneurohypophysial system are discussed.
Journal ArticleDOI
Aquaporins: Multiple Roles in the Central Nervous System
TL;DR: Intriguing possibilities suggest links for AQP1 in Alzheimer's disease, AQP4 as a target for therapy in brain edema, and a possible contribution of AQP9 in Parkinson's disease.
Journal ArticleDOI
Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release.
Nicola Romanò,Siew Hoong Yip,David J. Hodson,Anne Guillou,Anne Guillou,Sébastien Parnaudeau,Siobhan E Kirk,François Tronche,Xavier Bonnefont,Xavier Bonnefont,Paul Le Tissier,Stephen J. Bunn,Dave R. Grattan,Patrice Mollard,Patrice Mollard,Agnès O. Martin,Agnès O. Martin +16 more
TL;DR: Lactation represents a condition of decoupling between electrical activity at the cell body and DA secretion at the median eminence, at least in part attributable to lack of phosphorylation of tyrosine hydroxylase, the key enzyme involved in DA synthesis.
References
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Journal ArticleDOI
Expression of c-fos protein in brain: metabolic mapping at the cellular level
TL;DR: Fos immunohistochemistry provides a cellular method to label polysynaptically activated neurons and thereby map functional pathways in response to polysynaptic activation.
Journal ArticleDOI
A potent and selective endogenous agonist for the mu-opiate receptor.
TL;DR: The discovery and isolation from brain of a peptide, endomorphin-1 (Tyr-Pro-Trp-Phe-NH2), which has the highest specificity and affinity for the µ receptor of any endogenous substance so far described and they maybe natural ligands for this receptor.
Journal ArticleDOI
The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat
TL;DR: The autoradiographic material, and additional double-labeling experiments, were used to identify and to characterize projections that interconnect the A1, A2 and A6 regions, as well as possible projections from these cell groups to the spinal cord.
Journal ArticleDOI
The anatomy of neuropeptide-Y-containing neurons in rat brain.
Bibie M. Chronwall,Debora A. DiMaggio,V.J. Massari,V.J. Massari,Virginia M. Pickel,David A. Ruggiero,Thomas L. O'Donohue +6 more
TL;DR: The extremely high concentrations and widespread distribution of neuropeptide Y in the central nervous system suggests a number of important physiological roles for this neurotransmitter candidate.
Journal ArticleDOI
Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the rat.
TL;DR: The findings indicate that central catecholamine neurons can be subdivided into distinct sub-groups based upon the coexistence of a specific peptide.
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