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Journal ArticleDOI

Physiological Pathways Regulating the Activity of Magnocellular Neurosecretory Cells

Gareth Leng, +2 more
- 01 Apr 1999 - 
- Vol. 57, Iss: 6, pp 625-655
TLDR
This review considers the rôle played by particular afferent pathways in the regulation of the activity of oxytocin and vasopressin cells.
About
This article is published in Progress in Neurobiology.The article was published on 1999-04-01. It has received 307 citations till now. The article focuses on the topics: Vasopressin & Oxytocin.

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Citations
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Journal ArticleDOI

Long-term plasticity of postsynaptic GABAA-receptor function in the adult brain: insights from the oxytocin neurone.

TL;DR: It is argued that the hypothalamic oxytocin neurones provide an excellent model of both presynaptic and postsynaptic long-term plasticity of GABA-mediated transmission in the mature nervous system.
Journal ArticleDOI

Phasic spike patterning in rat supraoptic neurones in vivo and in vitro.

TL;DR: Analysis of hazard functions revealed that phasic firing in vitro appears consistent with a regenerative process arising from a relatively slow, late depolarizing afterpotential that approaches or exceeds spike threshold, and in vivo activity appears to be dominated by stochastic rather than deterministic mechanisms.
Journal ArticleDOI

Oxytocin and vasopressin: Social neuropeptides with complex neuromodulatory functions

TL;DR: Whereas both OXT and AVP promote social recognition, OXT also exerts anxiolytic and antidepressant effects whereas AVP promotes anxiety and stress response and these neuropeptides may have a role in psychiatric or neurologic disorders characterized by impaired social behavior and provide potential therapeutic targets in these conditions.
Journal ArticleDOI

Allopregnanolone in the brain: protecting pregnancy and birth outcomes

TL;DR: This review critically examines a role for allopregnanolone in both the maternal and foetal brain during pregnancy and development in protecting pregnancy and birth outcomes, with particular emphasis on its role in relation to stress exposure at this time.
Journal ArticleDOI

Oxytocin increases glucose uptake in neonatal rat cardiomyocytes.

TL;DR: The data suggest that OT and OT-GKR influence glucose uptake in neonatal rat CM and may thus play a role in the maintenance of cardiac function and cell survival during metabolic stress.
References
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Journal ArticleDOI

Expression of c-fos protein in brain: metabolic mapping at the cellular level

TL;DR: Fos immunohistochemistry provides a cellular method to label polysynaptically activated neurons and thereby map functional pathways in response to polysynaptic activation.
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A potent and selective endogenous agonist for the mu-opiate receptor.

TL;DR: The discovery and isolation from brain of a peptide, endomorphin-1 (Tyr-Pro-Trp-Phe-NH2), which has the highest specificity and affinity for the µ receptor of any endogenous substance so far described and they maybe natural ligands for this receptor.
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The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat

TL;DR: The autoradiographic material, and additional double-labeling experiments, were used to identify and to characterize projections that interconnect the A1, A2 and A6 regions, as well as possible projections from these cell groups to the spinal cord.
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The anatomy of neuropeptide-Y-containing neurons in rat brain.

TL;DR: The extremely high concentrations and widespread distribution of neuropeptide Y in the central nervous system suggests a number of important physiological roles for this neurotransmitter candidate.
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Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the rat.

TL;DR: The findings indicate that central catecholamine neurons can be subdivided into distinct sub-groups based upon the coexistence of a specific peptide.
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