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Journal ArticleDOI

Physiological Pathways Regulating the Activity of Magnocellular Neurosecretory Cells

Gareth Leng, +2 more
- 01 Apr 1999 - 
- Vol. 57, Iss: 6, pp 625-655
TLDR
This review considers the rôle played by particular afferent pathways in the regulation of the activity of oxytocin and vasopressin cells.
About
This article is published in Progress in Neurobiology.The article was published on 1999-04-01. It has received 307 citations till now. The article focuses on the topics: Vasopressin & Oxytocin.

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Citations
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Journal ArticleDOI

Role of hypothalamic corticotropin-releasing factor in mediating alcohol-induced activation of the rat hypothalamic-pituitary-adrenal axis.

TL;DR: It is likely that a better understanding of the mechanisms through which this drug stimulates the HPA axis may lead to the development of new therapies used in the treatment of alcohol abuse, including clinically relevant CRF antagonists.
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Temporal dissociation of the feedback effects of dendritically co-released peptides on rhythmogenesis in vasopressin cells

TL;DR: The temporal organisation of the feedback effects of these co-released peptides is different, with vasopressin effectively causing an immediate reduction in overall excitability whilst dynorphin causes a progressive decrease in post-spike excitability over the course of each burst.
Journal ArticleDOI

Facilitative role of endogenous oxytocin in noradrenaline release in the rat supraoptic nucleus

TL;DR: Data suggest that dendritic oxytocin facilitates activation of Oxytocin neurons, at least in part by augmentation of noradrenaline release via a presynaptic action.
Journal ArticleDOI

Serious adverse events associated with vasopressin and norepinephrine infusion in septic shock.

TL;DR: Serious adverse events associated with vasopressin and norepinephrine in patients who have septic shock are associated with increased mortality and morbidity.
Journal ArticleDOI

Dominant Role of βγ Subunits of G-Proteins in Oxytocin-Evoked Burst Firing

TL;DR: Gβγ subunits play a dominant role in burst firing evoked by applied OT or by suckling, supporting crucial roles for OTRs and Gαq/11 subunits in the milk-ejection reflex.
References
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Journal ArticleDOI

Expression of c-fos protein in brain: metabolic mapping at the cellular level

TL;DR: Fos immunohistochemistry provides a cellular method to label polysynaptically activated neurons and thereby map functional pathways in response to polysynaptic activation.
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A potent and selective endogenous agonist for the mu-opiate receptor.

TL;DR: The discovery and isolation from brain of a peptide, endomorphin-1 (Tyr-Pro-Trp-Phe-NH2), which has the highest specificity and affinity for the µ receptor of any endogenous substance so far described and they maybe natural ligands for this receptor.
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The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat

TL;DR: The autoradiographic material, and additional double-labeling experiments, were used to identify and to characterize projections that interconnect the A1, A2 and A6 regions, as well as possible projections from these cell groups to the spinal cord.
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The anatomy of neuropeptide-Y-containing neurons in rat brain.

TL;DR: The extremely high concentrations and widespread distribution of neuropeptide Y in the central nervous system suggests a number of important physiological roles for this neurotransmitter candidate.
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Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the rat.

TL;DR: The findings indicate that central catecholamine neurons can be subdivided into distinct sub-groups based upon the coexistence of a specific peptide.
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