Journal ArticleDOI
Physiological Pathways Regulating the Activity of Magnocellular Neurosecretory Cells
TLDR
This review considers the rôle played by particular afferent pathways in the regulation of the activity of oxytocin and vasopressin cells.About:
This article is published in Progress in Neurobiology.The article was published on 1999-04-01. It has received 307 citations till now. The article focuses on the topics: Vasopressin & Oxytocin.read more
Citations
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Journal ArticleDOI
The Oxytocin Receptor System: Structure, Function, and Regulation
Gerald Gimpl,Falk Fahrenholz +1 more
TL;DR: The regulation by gonadal and adrenal steroids is one of the most remarkable features of the OT system and is, unfortunately, the least understood.
Journal ArticleDOI
Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communication
Rainer Landgraf,Inga D. Neumann +1 more
TL;DR: This concept considers neuropeptides in the extracellular fluid of the brain rather than those in the cerebrospinal fluid or plasma as primary signals, triggering a variety of receptor-mediated effects, including those underlying behavioral and neuroendocrine regulation and psychopathology.
Journal ArticleDOI
Dendritic peptide release and peptide-dependent behaviours
Mike Ludwig,Gareth Leng +1 more
TL;DR: The recently demonstrated ability of neuropeptides to prime vesicle stores for activity-dependent release could lead to a temporary functional reorganization of neuronal networks harbouring specific peptide receptors, providing a substrate for long-lasting effects.
Journal ArticleDOI
Physiology of Vasopressin Relevant to Management of Septic Shock
TL;DR: Clinical use of vasopressin should await a randomized controlled trial of its effects on clinical outcomes such as organ failure and mortality, because clinical studies have been relatively small, focused on physiologic end points, and because of potential adverse effects of vasipressin.
Journal ArticleDOI
The hypothalamic-neurohypophysial system regulates the hypothalamic-pituitary-adrenal axis under stress: an old concept revisited.
TL;DR: Data supporting the concept of HNS effects on HPA axis activity is presented and their possible impact on some aspects of behavioural regulation and psychopathology is outlined.
References
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Journal ArticleDOI
Passive current flow and morphology in the terminal arborizations of the posterior pituitary
TL;DR: The information presented here about neurohypophysial nerve terminals should be useful in further investigations of how terminal arborization geometry and membrane properties influence neurosecretion and synaptic transmission.
Journal ArticleDOI
Local opioid inhibition and morphine dependence of supraoptic nucleus oxytocin neurones in the rat in vivo.
TL;DR: The acute inhibition of supraoptic nucleus oxytocin neurones which results from systemic administration of opioid agonists primarily occurs within the supraopti nucleus itself, since the antagonist naloxone was effective when given into the supraOptic nucleus.
Journal Article
Anterior third ventricle (A3V) lesions and homeostasis regulation.
Chiaraviglio E,Pérez Guaita Mf +1 more
TL;DR: The results suggest that A3V lesioned animals fall to regulate fluids and electrolyte homeostasis, perhaps by disruption of an inhibitory feed back loop between the OVLT and other circumventricular structures.
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Effects of intracerebroventricular clonidine on the hypothalamic noradrenaline and plasma corticosterone levels of opiate naive rats and after naloxone-induced withdrawal.
TL;DR: The results show an interaction between opioid-receptors and alpha 2-adrenoceptors in the hypothalamus, and suggest that mechanisms other than hyperactivity of NA neurons contribute to the HPA axis hyperactivity during the opiate withdrawal.
Journal ArticleDOI
The role of the AV3V region in the control of magnocellular oxytocin neurons.
TL;DR: While supraoptic neurons are directly osmosensitive, the AV3V region is essential for their normal osmoresponsiveness and is not involved in the activation of oxytocin neurons during suckling or parturition.
Related Papers (5)
Dendrites of hypothalamic magnocellular neurons release neurohypophysial peptides by exocytosis.
David V. Pow,John F. Morris +1 more