Journal ArticleDOI
Physiological Pathways Regulating the Activity of Magnocellular Neurosecretory Cells
TLDR
This review considers the rôle played by particular afferent pathways in the regulation of the activity of oxytocin and vasopressin cells.About:
This article is published in Progress in Neurobiology.The article was published on 1999-04-01. It has received 307 citations till now. The article focuses on the topics: Vasopressin & Oxytocin.read more
Citations
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Journal ArticleDOI
The Oxytocin Receptor System: Structure, Function, and Regulation
Gerald Gimpl,Falk Fahrenholz +1 more
TL;DR: The regulation by gonadal and adrenal steroids is one of the most remarkable features of the OT system and is, unfortunately, the least understood.
Journal ArticleDOI
Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communication
Rainer Landgraf,Inga D. Neumann +1 more
TL;DR: This concept considers neuropeptides in the extracellular fluid of the brain rather than those in the cerebrospinal fluid or plasma as primary signals, triggering a variety of receptor-mediated effects, including those underlying behavioral and neuroendocrine regulation and psychopathology.
Journal ArticleDOI
Dendritic peptide release and peptide-dependent behaviours
Mike Ludwig,Gareth Leng +1 more
TL;DR: The recently demonstrated ability of neuropeptides to prime vesicle stores for activity-dependent release could lead to a temporary functional reorganization of neuronal networks harbouring specific peptide receptors, providing a substrate for long-lasting effects.
Journal ArticleDOI
Physiology of Vasopressin Relevant to Management of Septic Shock
TL;DR: Clinical use of vasopressin should await a randomized controlled trial of its effects on clinical outcomes such as organ failure and mortality, because clinical studies have been relatively small, focused on physiologic end points, and because of potential adverse effects of vasipressin.
Journal ArticleDOI
The hypothalamic-neurohypophysial system regulates the hypothalamic-pituitary-adrenal axis under stress: an old concept revisited.
TL;DR: Data supporting the concept of HNS effects on HPA axis activity is presented and their possible impact on some aspects of behavioural regulation and psychopathology is outlined.
References
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Journal ArticleDOI
Action of endogenous oxytocin within the paraventricular or supraoptic nuclei : a powerful link in the regulation of the bursting pattern of oxytocin neurons during the milk-ejection reflex in rats
TL;DR: It is suggested that the recruitment of a critical number of oxytocin neurons within one nucleus induces changes in the bursting activity of the oxytoc in neurons in the four magnocellular nuclei.
Journal ArticleDOI
Oxytocin receptors on oxytocin neurones: histoautoradiographic detection in the lactating rat.
TL;DR: Combined application of histoautoradiographic and immunohistochemical techniques showed that the OT binding sites were concentrated on OT magnocellular neurones, and probably mediate the facilitatory effect of OT on its own release during the milk ejection reflex.
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Ultrastructural evidence for intra- and extranuclear projections of GABAergic neurons of the suprachiasmatic nucleus.
TL;DR: The present results indicate that the SCN may utilize this inhibitory neurotransmitter to regulate and organize its own circadian rhythm as well as using GABA to transmit its diurnal information to other regions of the brain.
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Clonidine infusions into the locus coeruleus attenuate behavioral and neurochemical changes associated with naloxone-precipitated withdrawal.
TL;DR: Behavioral and biochemical evidence is provided to support the suggestion that clonidine significantly attenuates naloxone-precipitated withdrawal through an interaction with noradrenergic neurons located in the vicinity of the LC.
Journal ArticleDOI
Naloxone prevents interruption of parturition and increases plasma oxytocin following environmental disturbance in parturient sows
Alistair Lawrence,J.Carol Petherick,KA McLean,C.L Gilbert,Christopher L. Chapman,John A. Russell +5 more
TL;DR: Plasma concentrations of oxytocin in primiparous female pigs with chronic catheters preplaced in the external jugular vein were significantly lower than in naloxone-treated pigs, five out of six of which gave birth spontaneously to one or more piglets within 2.5 h.
Related Papers (5)
Dendrites of hypothalamic magnocellular neurons release neurohypophysial peptides by exocytosis.
David V. Pow,John F. Morris +1 more