Journal ArticleDOI
Physiological Pathways Regulating the Activity of Magnocellular Neurosecretory Cells
TLDR
This review considers the rôle played by particular afferent pathways in the regulation of the activity of oxytocin and vasopressin cells.About:
This article is published in Progress in Neurobiology.The article was published on 1999-04-01. It has received 307 citations till now. The article focuses on the topics: Vasopressin & Oxytocin.read more
Citations
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Development of G-quadruplex Stabilizers as Anticancer Drug Therapy and Selective Agonists of the Human Oxytocin Receptor as a Therapeutic Tool for Neuropsychiatric Disorders
TL;DR: This dissertation will describe two different approaches to the successful identification of small-molecules that interact with their validated targets, including the identification of new G-quadruplex stabilizers and their ability to inhibit human telomerase as an anticancer drug modality.
Journal ArticleDOI
V2 vasopressin receptor mutations: future personalized therapy based on individual molecular biology
TL;DR: In this article , the authors provide an overview of recent findings about the potential therapeutic interventions in the light of the current experimental data, and provide a review of the most relevant studies.
Journal ArticleDOI
Detecting the subthreshold signal in a neural network via statistical complexity measure
TL;DR: In this article , the authors proposed an information theory approach for detecting the subthreshold signal in a small-world network composed of Fitz Hugh-Nagumo (FHN) neurons.
CALL FOR PAPERS Neurohypophyseal Hormones: From Genomics and Physiology to Disease Activity-dependent feedback modulation of spike patterning of supraoptic nucleus neurons by endogenous adenosine
TL;DR: Microdialysis application of the A1 receptor antagonist, 8-cyclopentyl-1,3-dimethylxanthine (CPT) increased phasic vasopressin cell intraburst firing rates progressively over the first 5 s, and increased burst duration, indicating that endogenous adenosine is involved in the local control of SON cell activity in vivo.
References
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Journal ArticleDOI
Expression of c-fos protein in brain: metabolic mapping at the cellular level
TL;DR: Fos immunohistochemistry provides a cellular method to label polysynaptically activated neurons and thereby map functional pathways in response to polysynaptic activation.
Journal ArticleDOI
A potent and selective endogenous agonist for the mu-opiate receptor.
TL;DR: The discovery and isolation from brain of a peptide, endomorphin-1 (Tyr-Pro-Trp-Phe-NH2), which has the highest specificity and affinity for the µ receptor of any endogenous substance so far described and they maybe natural ligands for this receptor.
Journal ArticleDOI
The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat
TL;DR: The autoradiographic material, and additional double-labeling experiments, were used to identify and to characterize projections that interconnect the A1, A2 and A6 regions, as well as possible projections from these cell groups to the spinal cord.
Journal ArticleDOI
The anatomy of neuropeptide-Y-containing neurons in rat brain.
Bibie M. Chronwall,Debora A. DiMaggio,V.J. Massari,V.J. Massari,Virginia M. Pickel,David A. Ruggiero,Thomas L. O'Donohue +6 more
TL;DR: The extremely high concentrations and widespread distribution of neuropeptide Y in the central nervous system suggests a number of important physiological roles for this neurotransmitter candidate.
Journal ArticleDOI
Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the rat.
TL;DR: The findings indicate that central catecholamine neurons can be subdivided into distinct sub-groups based upon the coexistence of a specific peptide.
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