Journal ArticleDOI
Physiological Pathways Regulating the Activity of Magnocellular Neurosecretory Cells
TLDR
This review considers the rôle played by particular afferent pathways in the regulation of the activity of oxytocin and vasopressin cells.About:
This article is published in Progress in Neurobiology.The article was published on 1999-04-01. It has received 307 citations till now. The article focuses on the topics: Vasopressin & Oxytocin.read more
Citations
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Journal ArticleDOI
The Oxytocin Receptor System: Structure, Function, and Regulation
Gerald Gimpl,Falk Fahrenholz +1 more
TL;DR: The regulation by gonadal and adrenal steroids is one of the most remarkable features of the OT system and is, unfortunately, the least understood.
Journal ArticleDOI
Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communication
Rainer Landgraf,Inga D. Neumann +1 more
TL;DR: This concept considers neuropeptides in the extracellular fluid of the brain rather than those in the cerebrospinal fluid or plasma as primary signals, triggering a variety of receptor-mediated effects, including those underlying behavioral and neuroendocrine regulation and psychopathology.
Journal ArticleDOI
Dendritic peptide release and peptide-dependent behaviours
Mike Ludwig,Gareth Leng +1 more
TL;DR: The recently demonstrated ability of neuropeptides to prime vesicle stores for activity-dependent release could lead to a temporary functional reorganization of neuronal networks harbouring specific peptide receptors, providing a substrate for long-lasting effects.
Journal ArticleDOI
Physiology of Vasopressin Relevant to Management of Septic Shock
TL;DR: Clinical use of vasopressin should await a randomized controlled trial of its effects on clinical outcomes such as organ failure and mortality, because clinical studies have been relatively small, focused on physiologic end points, and because of potential adverse effects of vasipressin.
Journal ArticleDOI
The hypothalamic-neurohypophysial system regulates the hypothalamic-pituitary-adrenal axis under stress: an old concept revisited.
TL;DR: Data supporting the concept of HNS effects on HPA axis activity is presented and their possible impact on some aspects of behavioural regulation and psychopathology is outlined.
References
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Journal ArticleDOI
Clonidine but not nifedipine prevents the release of noradrenaline during naloxone-precipitated opiate withdrawal: an in vivo microdialysis study in the rat
TL;DR: It is suggested that whilst the action of clonidine in attenuating the morphine withdrawal syndrome may be mediated by decreasing central noradrenline release, this is not the mechanism by which nifedipine acts.
Journal ArticleDOI
Vasopressin-induced pressor response elicited by electrical stimulation of solitary nucleus and dorsal motor nucleus of vagus of rat
TL;DR: Electrical stimulation of the solitary nucleus and dorsal motor nucleus of the vagus eliciting a pressor response in vagotomized rat with the spinal cord cut at C1 was entirely accounted for by an increased release of vasopressin upon stimulation.
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Endogenous opioid regulation of oxytocin release during parturition is reduced in ovariectomized rats.
TL;DR: It is concluded that the decreased oxytocin concentrations prepartum, the prolongation of parturition and the decrease in opioid tone in ovariectomized steroid-treated rats may be partly due to a lack of relaxin produced by the ovary.
Journal ArticleDOI
Electrophysiological evidence for retinal projections to the hypothalamic supraoptic nucleus and its perinuclear zone.
TL;DR: The electrophysiological methods investigated the projections from the optic nerve to the supraoptic nucleus (SON) and its perinuclear zone (PNZ) which might underlie the rhythm and suggest a role for the PNZ in this input.
Journal ArticleDOI
Cholinergic excitation of supraoptic neurons in hypothalamic slices of rat.
TL;DR: Evidence is provided that nicotinic receptors can mediate cholinergic influences on cells of the supraoptic nucleus and the excitations by NIC showed densensitization, which may subserve a modulatory role to other transmitters in the supraOptic nucleus.
Related Papers (5)
Dendrites of hypothalamic magnocellular neurons release neurohypophysial peptides by exocytosis.
David V. Pow,John F. Morris +1 more