SARS-CoV-2 Seroprevalence in Household Domestic Ferrets ( Mustela putorius furo ).
Jacobo Giner,Sergio Villanueva-Saz,Ana P. Tobajas,María D. Pérez,Ana Rodríguez González,M. T. Verde,Andrés Yzuel,Ana García-García,Víctor Taleb,Erandi Lira-Navarrete,Ramon Hurtado-Guerrero,Julián Pardo,Llipsy Santiago,José Ramón Paño,Héctor Ruiz,Delia Lacasta,Antonio Fernández +16 more
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TLDR
The evidence of household pet ferrets exposure to SARS-CoV-2 in Spain to date is reported for the first time, and anti-RBD Sars-Cov-2 antibodies persisted at detectable levels in a seropositive SARS, CoV,2 domestic ferret beyond 129 days since the first-time antibodies were detected.Abstract:
Animal infections with SARS-CoV-2 have been reported in different countries and several animal species have been proven to be susceptible to infection with SARS-CoV-2 both naturally and by experimental infection. Moreover, infections under natural conditions in more than 20 mink farms have been reported where humans could have been the source of infection for minks. However, little information is available about the susceptibility of pet animals under natural conditions and currently there is no SARS-CoV-2 epidemiological assessment occurrence in household ferrets. In this study, the presence of SARS-CoV-2 antibodies was evaluated in serum samples obtained from 127 household ferrets (Mustela putorius furo) in the Province of Valencia (Spain). Two ferrets tested positive to SARS-CoV-2 (1.57%) by in-house enzyme-linked immunosorbent assay based on receptor binding domain (RBD) of Spike antigen. Furthermore, anti-RBD SARS-CoV-2 antibodies persisted at detectable levels in a seropositive SARS-CoV-2 domestic ferret beyond 129 days since the first time antibodies were detected. This study reports for the first time the evidence of household pet ferrets exposure to SARS-CoV-2 in Spain to date.read more
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SARS-CoV-2 in animals: potential for unknown reservoir hosts and public health implications.
Khan Sharun,Kuldeep Dhama,A.M. Pawde,Christian Gortázar,Ruchi Tiwari,D. Katterine Bonilla-Aldana,Alfonso J. Rodriguez-Morales,José de la Fuente,José de la Fuente,Izabela Michalak,Youssef A. Attia,Youssef A. Attia +11 more
TL;DR: In this article, a review analyzes the current evidence of SARS-CoV-2 natural infection in domestic and wild animal species and their possible implications on public health, which may eventually act as viral reservoirs.
Journal ArticleDOI
Adaptation, spread and transmission of SARS-CoV-2 in farmed minks and associated humans in the Netherlands.
Lu Lu,Reina S. Sikkema,Francisca C. Velkers,David F. Nieuwenhuijse,Egil A.J. Fischer,Paola A. Meijer,Noortje Bouwmeester-Vincken,Ariene Rietveld,M. C. A. Wegdam-Blans,Paulien Tolsma,Marco Koppelman,Lidwien A.M. Smit,Renate W. Hakze-van der Honing,Wim H.M. van der Poel,Arco N. van der Spek,Marcel A.H. Spierenburg,Robert Jan Molenaar,Jan de Rond,Marieke Augustijn,Mark E. J. Woolhouse,J. Arjan Stegeman,Samantha Lycett,Bas B. Oude Munnink,Marion Koopmans +23 more
TL;DR: In this article, the first wave of the COVID-19 pandemic (April 2020) was detected in farmed minks and genomic sequencing was performed on mink farms and farm personnel.
Journal ArticleDOI
First Description of SARS-CoV-2 Infection in Two Feral American Mink (Neovison vison) Caught in the Wild.
Jordi Aguiló-Gisbert,Miguel Padilla-Blanco,Victor Lizana,Elisa Maiques,Marta Muñoz-Baquero,Eva Chillida-Martínez,Jesús Cardells,Consuelo Rubio-Guerri +7 more
TL;DR: In this article, the authors reported the detection of SARS-CoV-2 in 2 of 13 American mink (Neovison vison) trapped in the Valencian Community (Eastern Spain), during an invasive species trapping campaign.
Journal ArticleDOI
SARS-CoV-2 evolution in animals suggests mechanisms for rapid variant selection.
Laura Bashor,Roderick B. Gagne,Angela M. Bosco-Lauth,Richard A. Bowen,Mark D. Stenglein,Sue VandeWoude +5 more
TL;DR: In this paper, the authors sequenced full genomes of Vero cell-expanded SARS-CoV-2 inoculum and viruses recovered from cats (n = 6), dogs, cats, and hamsters within 1-to-3-d postexposure.
Journal ArticleDOI
Natural and Experimental SARS-CoV-2 Infection in Domestic and Wild Animals.
TL;DR: In this paper, the authors summarized the current findings regarding the susceptibility of different domestic and wild animal species to experimental SARS-CoV-2 infection and provided detailed descriptions of the clinical disease and transmissibility in these animals.
References
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Protease inhibitors broadly effective against feline, ferret and mink coronaviruses
Krishani Dinali Perera,Anushka C. Galasiti Kankanamalage,A.D. Rathnayake,Amanda Honeyfield,William C. Groutas,Kyeong-Ok Chang,Yunjeong Kim +6 more
TL;DR: Small molecule compounds show potent activity against 3C‐like proteases of feline, ferret and mink coronaviruses in vitro, providing support for further research to develop broad‐spectrum antiviral agents for multiple coronavirus infections.
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Infectivity, virulence, pathogenicity, host-pathogen interactions of SARS and SARS-CoV-2 in experimental animals: a systematic review.
TL;DR: The pathogenicity, transmission, variations in angiotensin-converting-enzyme 2 receptor-binding across species and host pathogen interactions of SARS and SARS-CoV-2 in laboratory animals used in research are discussed.
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Two Cases of Systemic Coronavirus-Associated Disease Resembling Feline Infectious Peritonitis in Domestic Ferrets in Japan
TL;DR: 2 cases of systemic coronavirus-associated disease in ferrets presented to Japanese veterinary hospitals are described, and both cases tested positive for coronav virus antigen by IHC.
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