Book ChapterDOI
The Definition and Prevalence of Obesity and Metabolic Syndrome.
TLDR
Obesity is associated with a large decrease in life expectancy, but up to 30% of obese patients are metabolically healthy with insulin sensitivity similar to healthy normal weight individuals, lower visceral fat content, and lower intima media thickness of the carotid artery than the majority of metabolically "unhealthy" obese patients.Abstract:
Increase in prevalence of obesity has become a worldwide major health problem in adults, as well as among children and adolescents. Furthermore, total adiposity and truncal subcutaneous fat accumulation during adolescence are positively and independently associated with atherosclerosis at adult ages. Centrally accumulation of body fat is associated with insulin resistance, whereas distribution of body fat in a peripheral pattern is metabolically less important. Obesity is associated with a large decrease in life expectancy. The effect of extreme obesity on mortality is greater among younger than older adults. In this respect, obesity is also associated with increased risk of several cancer types. However, up to 30% of obese patients are metabolically healthy with insulin sensitivity similar to healthy normal weight individuals, lower visceral fat content, and lower intima media thickness of the carotid artery than the majority of metabolically “unhealthy” obese patients.read more
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Journal ArticleDOI
Changes in aortic diameter induced by weight loss: The HELENA trial- whole-body MR imaging in a dietary intervention trial
Sibylle Stoll,Solomon A Sowah,Mathias Fink,T. S. Nonnenmacher,Mirja E. Graf,Theron Johnson,Christopher L. Schlett,Oyunbileg von Stackelberg,Romy Kirsten,Fabian Bamberg,Jeffrey N. Keller,Cornelia M. Ulrich,Rudolf Kaaks,Hans-Ulrich Kauczor,Fabian Rengier,Tilman Kühn,Johanna Nattenmüller +16 more
TL;DR: Aortic diameters were positively associated with weight, visceral adipose tissue, glucose, HbA1c and with both systolic and diastolic blood pressure and weight loss induced by calorie restriction may reduce aorti diameters.
Journal ArticleDOI
Prevalencia de sobrepeso, obesidad, y sus factores de riesgo en niños de 7 a 12 años en una escuela pública de Cartagena – Colombia
TL;DR: In a recent study as discussed by the authors , the prevalencia de sobrepeso and obesidad, and factores of riesgo in niños of 7-12 años, were investigated in 269 escolares of una institución educativa de Cartagena, Colombia.
Journal ArticleDOI
Feasibility and efficacy of a technology-based weight loss intervention program through public-private partnerships in Japan
Seika Kamohara,Yoshiko Terasaki,Sachiyo Tomita,Rika Kishino,Sayaka Kanmuri,Hiroe Ajioka,Hiromichi Seki +6 more
Journal ArticleDOI
Supplementation with okra combined or not with exercise training is able to protect the heart of animals with metabolic syndrome
Moisés Felipe Pereira Gomes,Elizabeth de Orleans Carvalho de Moura,Naiara Magalhães Cardoso,Graziele Aparecida da Silva,Ana Carolina Cardoso dos Santos,Fernanda Samantha de Souza,Debora Estadella,Rafael Herling Lambertucci,João Henrique G. Lago,Alessandra Medeiros +9 more
TL;DR: In this paper , the authors evaluated the effect of O consumption and exercise training on metabolic syndrome (MetS) in animals with 10-week-old male Zucker rats and found that O consumption alone was able to promote improved insulin sensitivity and reduced systolic blood pressure.
References
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Journal ArticleDOI
Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Scott M. Grundy,David W. Bilheimer,Alan Chait,Luther T. Clark,Margo A. Denke,Richard J. Havel,William R. Hazzard,Stephen B. Hulley,Donald B. Hunninghake,Robert A. Kreisberg,Penny M. Kris-Etherton,James M. McKenney,Michael A. Newman,Ernst J. Schaefer,Burton E. Sobel,Carolyn Somelofski,Milton C. Weinstein,H. Bryan Brewer,James I. Cleeman,Karen A. Donato,Nancy D. Ernst,Jeffrey M. Hoeg,Basil M. Rifkind,Jacques E. Rossouw,Christopher T. Sempos,Joanne M. Gallivan,Maureen N. Harris,Laurie Quint-Adler +27 more
TL;DR: Dairy therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD, and the fundamental approach to treatment is comparable.
Journal ArticleDOI
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation.
K. G. M. M. Alberti,Paul Zimmet +1 more
TL;DR: A WHO Consultation has taken place in parallel with a report by an American Diabetes Association Expert Committee to re‐examine diagnostic criteria and classification of diabetes mellitus and is hoped that the new classification will allow better classification of individuals and lead to fewer therapeutic misjudgements.
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Detection, Evaluation, and Treatment of High Blood Cholesterol Education Program (NCEP) Expert Panel on Executive Summary of the Third Report of the National
William C. Taylor,Nigel Unwin +1 more
Journal Article
Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Scott M. Grundy,Diane M. Becker,Luther T. Clark,Richard S. Cooper,Margo A. Denke,James P. Howard,Donald B. Hunninghake,D. Roger Illingworth,Russell V. Luepker,Patrick E. McBride,James M. McKenney,Richard C. Pasternak,Neil J. Stone,Linda Van Horn +13 more
Journal ArticleDOI
Diagnosis and Management of the Metabolic Syndrome An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
Scott M. Grundy,James I. Cleeman,Stephen R. Daniels,Karen A. Donato,Robert H. Eckel,Barry A. Franklin,David Gordon,Ronald M. Krauss,Peter J. Savage,Sidney C. Smith,John A. Spertus,Fernando Costa +11 more
TL;DR: This statement from the American Heart Association and the National Heart, Lung, and Blood Institute is intended to provide up-to-date guidance for professionals on the diagnosis and management of the metabolic syndrome in adults.
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