Book ChapterDOI
The Definition and Prevalence of Obesity and Metabolic Syndrome.
TLDR
Obesity is associated with a large decrease in life expectancy, but up to 30% of obese patients are metabolically healthy with insulin sensitivity similar to healthy normal weight individuals, lower visceral fat content, and lower intima media thickness of the carotid artery than the majority of metabolically "unhealthy" obese patients.Abstract:
Increase in prevalence of obesity has become a worldwide major health problem in adults, as well as among children and adolescents. Furthermore, total adiposity and truncal subcutaneous fat accumulation during adolescence are positively and independently associated with atherosclerosis at adult ages. Centrally accumulation of body fat is associated with insulin resistance, whereas distribution of body fat in a peripheral pattern is metabolically less important. Obesity is associated with a large decrease in life expectancy. The effect of extreme obesity on mortality is greater among younger than older adults. In this respect, obesity is also associated with increased risk of several cancer types. However, up to 30% of obese patients are metabolically healthy with insulin sensitivity similar to healthy normal weight individuals, lower visceral fat content, and lower intima media thickness of the carotid artery than the majority of metabolically “unhealthy” obese patients.read more
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Journal ArticleDOI
Effects of an Online Supervised Exercise Training in Children with Obesity during the COVID-19 Pandemic
TL;DR: In this paper , the effects of a 12-week online supervised training program in children with obesity on different PF components and PA levels were evaluated using a series of anthropometric measures, the PAQ-C questionnaire and PF tests, valid and reliable tools to assess PF in children.
Journal ArticleDOI
Self-Reported Physical Fitness in Children and Adolescents with Obesity: A Cross-Sectional Analysis on the Level of Alignment with Multiple Adiposity Indexes
Matteo Vandoni,Nicola Lovecchio,Vittoria Carnevale Pellino,Roberto Codella,Valentina Fabiano,Virginia Rossi,Gian Vincenzo Zuccotti,Valeria Calcaterra +7 more
TL;DR: In this article, the International Fitness Enjoyment Scale (IFIS) questionnaire was administered to 200 overweight and normal weight (NW) children to investigate the existence of differences between self-reported physical fitness in children with obesity compared to normal weight.
Journal ArticleDOI
3D analysis of capillary network in skeletal muscle of obese insulin-resistant mice
Nejc Umek,Simon Horvat,Erika Cvetko,Marko Kreft,Jiří Janáček,Lucie Kubínová,Tatjana Stopar Pintaric,Tatjana Stopar Pintaric,Ida Eržen +8 more
TL;DR: The results show that obese insulin-resistant mice have selective increase in capillarization around small predominantly intermediate muscle fibres, which is most likely related to the impaired glucose metabolism characteristic of type 2 diabetes.
Journal ArticleDOI
HOMA-IR for predicting clinical pregnancy rate during IVF.
TL;DR: In this article, the cutoff values of HOMA-IR for predicting clinical pregnancy rate in normal weight patients during their first IVF were determined for 329 normal-weight women.
Journal ArticleDOI
Overweight/obesity in adolescents with phenylketonuria: Protective and predisposing factors.
Adriana M. Silveira,Poliane Lopes Lima,Michelle Rosa Andrade Alves,Rosângelis D. L. Soares,Viviane de Cássia Kanufre,Valéria de Melo Rodrigues,Ana Lúcia Pimenta Starling,Rocksane de Carvalho Norton,Marcos José Burle de Aguiar +8 more
TL;DR: In this paper, anthropometric measurements, serum phenylalanine levels, and 10 metabolites associated with lipid and carbohydrate metabolism were analyzed in 101 adolescents aged 10-20 years and classified into overweight/obesity and eutrophic/low body mass index groups.
References
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Journal ArticleDOI
Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
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TL;DR: Dairy therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD, and the fundamental approach to treatment is comparable.
Journal ArticleDOI
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation.
K. G. M. M. Alberti,Paul Zimmet +1 more
TL;DR: A WHO Consultation has taken place in parallel with a report by an American Diabetes Association Expert Committee to re‐examine diagnostic criteria and classification of diabetes mellitus and is hoped that the new classification will allow better classification of individuals and lead to fewer therapeutic misjudgements.
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Detection, Evaluation, and Treatment of High Blood Cholesterol Education Program (NCEP) Expert Panel on Executive Summary of the Third Report of the National
William C. Taylor,Nigel Unwin +1 more
Journal Article
Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Scott M. Grundy,Diane M. Becker,Luther T. Clark,Richard S. Cooper,Margo A. Denke,James P. Howard,Donald B. Hunninghake,D. Roger Illingworth,Russell V. Luepker,Patrick E. McBride,James M. McKenney,Richard C. Pasternak,Neil J. Stone,Linda Van Horn +13 more
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Diagnosis and Management of the Metabolic Syndrome An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
Scott M. Grundy,James I. Cleeman,Stephen R. Daniels,Karen A. Donato,Robert H. Eckel,Barry A. Franklin,David Gordon,Ronald M. Krauss,Peter J. Savage,Sidney C. Smith,John A. Spertus,Fernando Costa +11 more
TL;DR: This statement from the American Heart Association and the National Heart, Lung, and Blood Institute is intended to provide up-to-date guidance for professionals on the diagnosis and management of the metabolic syndrome in adults.
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