Book ChapterDOI
The Definition and Prevalence of Obesity and Metabolic Syndrome.
TLDR
Obesity is associated with a large decrease in life expectancy, but up to 30% of obese patients are metabolically healthy with insulin sensitivity similar to healthy normal weight individuals, lower visceral fat content, and lower intima media thickness of the carotid artery than the majority of metabolically "unhealthy" obese patients.Abstract:
Increase in prevalence of obesity has become a worldwide major health problem in adults, as well as among children and adolescents. Furthermore, total adiposity and truncal subcutaneous fat accumulation during adolescence are positively and independently associated with atherosclerosis at adult ages. Centrally accumulation of body fat is associated with insulin resistance, whereas distribution of body fat in a peripheral pattern is metabolically less important. Obesity is associated with a large decrease in life expectancy. The effect of extreme obesity on mortality is greater among younger than older adults. In this respect, obesity is also associated with increased risk of several cancer types. However, up to 30% of obese patients are metabolically healthy with insulin sensitivity similar to healthy normal weight individuals, lower visceral fat content, and lower intima media thickness of the carotid artery than the majority of metabolically “unhealthy” obese patients.read more
Citations
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Journal ArticleDOI
Cardiac Remodeling During Pregnancy With Metabolic Syndrome: Prologue of Pathological Remodeling.
Yijun Yang,Justin Kurian,Giana Schena,Jaslyn Johnson,Hajime Kubo,Joshua G. Travers,Chunya Kang,Anna Maria Lucchese,Deborah M Eaton,Maoting Lv,Na Li,Lorianna G. Leynes,Daohai Yu,Fengzhen Yang,Timothy A. McKinsey,Raj Kishore,Mohsin Khan,Sadia Mohsin,Steven R. Houser +18 more
TL;DR: In this article, the heart undergoes physiological hypertrophy during pregnancy in healthy individuals and Metabolic syndrome (MetS) is now prevalent in women of childbearing age and might add risks of ad...
Journal ArticleDOI
High prevalence of childhood overweight and obesity in ten Caribbean countries: 2018 cross-sectional data and a narrative review of trends in Trinidad and Tobago
Kirin Rambaran,Surujpal Teelucksingh,Sesh Gowrie Sankar,Michael S. Boyne,Godfrey Xuereb,Ambra Giorgetti,Michael B. Zimmermann +6 more
TL;DR: There is an alarmingly high prevalence of childhood obesity across the Caribbean, and within the last two decades, the percentage of overweight and obese school-children in Trinidad and Tobago has increased four-fold, likely reflecting a decline in physical activity and rise in sedentary behaviour.
Journal ArticleDOI
A Cecropia peltata ethanolic extract reduces insulin resistance and hepatic steatosis in rats fed a high-fat diet.
Andrea Duarte-Alonso,Trinidad Eugenia Cu-Cañetas,Azalia Avila-Nava,Delia Sansores-España,Juan José Acevedo-Fernández,Mukthar Sandoval-Peraza,Luis Chel-Guerrero,Ivan Torre-Villalvazo +7 more
TL;DR: Administration of a CP extract prevented glucose intolerance and hepatic lipid accumulation in rats fed a HFD in association with reduced adipocyte hypertrophy, demonstrating potential antidiabetic properties.
Journal ArticleDOI
Effects of microwave technology on the subcutaneous abdominal fat and anthropometric indices of overweight adults: A clinical trial
Naseh Pahlavani,Elyas Nattagh-Eshtivani,Alireza Amanollahi,Golnaz Ranjbar,Hamid Asadzadeh Aghdaei,Jamshid Gholizadeh Navashenaq,Zeinab Shabaninezhad,Najibeh Razgardani Sharahi,Moona Maleki,Mahsa Malekahmadi,Abdolreza Norouzy +10 more
TL;DR: In this paper, the effects of microwave technology on abdominal obesity and anthropometric indices of overweight adults were evaluated in a clinical trial on 53 overweight adults aged 18-65 years who referred to Behbood Clinic in Tehran, Iran.
Dissertation
Molecular pathology : the roles of P53 in the oxidative stress and DNA damage responses in chronic liver disease and hepatocellular carcinoma
TL;DR: This paper aims to provide a chronology of the events leading up to and including the publication of the will and aims to clarify the specific events that led to its publication.
References
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Journal ArticleDOI
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TL;DR: Dairy therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD, and the fundamental approach to treatment is comparable.
Journal ArticleDOI
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation.
K. G. M. M. Alberti,Paul Zimmet +1 more
TL;DR: A WHO Consultation has taken place in parallel with a report by an American Diabetes Association Expert Committee to re‐examine diagnostic criteria and classification of diabetes mellitus and is hoped that the new classification will allow better classification of individuals and lead to fewer therapeutic misjudgements.
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Detection, Evaluation, and Treatment of High Blood Cholesterol Education Program (NCEP) Expert Panel on Executive Summary of the Third Report of the National
William C. Taylor,Nigel Unwin +1 more
Journal Article
Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Scott M. Grundy,Diane M. Becker,Luther T. Clark,Richard S. Cooper,Margo A. Denke,James P. Howard,Donald B. Hunninghake,D. Roger Illingworth,Russell V. Luepker,Patrick E. McBride,James M. McKenney,Richard C. Pasternak,Neil J. Stone,Linda Van Horn +13 more
Journal ArticleDOI
Diagnosis and Management of the Metabolic Syndrome An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
Scott M. Grundy,James I. Cleeman,Stephen R. Daniels,Karen A. Donato,Robert H. Eckel,Barry A. Franklin,David Gordon,Ronald M. Krauss,Peter J. Savage,Sidney C. Smith,John A. Spertus,Fernando Costa +11 more
TL;DR: This statement from the American Heart Association and the National Heart, Lung, and Blood Institute is intended to provide up-to-date guidance for professionals on the diagnosis and management of the metabolic syndrome in adults.
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