Journal ArticleDOI
The immune system, adaptation, and machine learning
TLDR
A dynamical model for the immune system is described that is based on the network hypothesis of Jerne, and is simple enough to simulate on a computer, and has a strong similarity to an approach to learning and artificial intelligence introduced by Holland, called the classifier system.About:
This article is published in Physica D: Nonlinear Phenomena.The article was published on 1986-10-01. It has received 1326 citations till now. The article focuses on the topics: Artificial immune system & Learning classifier system.read more
Citations
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Journal ArticleDOI
Test of a statistical model for molecular recognition in biological repertoires.
TL;DR: The RAD model is found to provide the best description for binding data for over eight orders of magnitude on the affinity scale, and to account for a relationship between repertoire size and the maximal obtainable affinity within different repertoires, which points to a potential universality of the rules that govern affinity distributions in biology.
Journal ArticleDOI
Efficient combined immune-decomposition algorithm for optimal buffer allocation in production lines for throughput and profit maximization
TL;DR: A combined artificial immune system optimization algorithm in conjunction with a decomposition method to optimally allocate buffers in transfer lines to achieve optimal system performance under buffers space constraints is implemented.
Proceedings ArticleDOI
Hardware fault tolerance: an immunological solution
D.W. Bradley,Andy M. Tyrrell +1 more
TL;DR: The proposed methods demonstrate how through a process of self/non-self-differentiation, the hardware immune system creates a set of tolerance conditions to monitor the change in states of the hardware.
Journal ArticleDOI
Parameter free Jaya algorithm for truss sizing-layout optimization under natural frequency constraints
TL;DR: Optimization results prove the superiority of PFJA over standard JA, MJA and other metaheuristic optimizers available in the literature.
References
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Journal ArticleDOI
Somatic generation of antibody diversity
TL;DR: In the genome of a germ-line cell, the genetic information for an immunoglobulin polypeptide chain is contained in multiple gene segments scattered along a chromosome which are assembled by recombination which leads to the formation of a complete gene.
Book ChapterDOI
A mathematical model illustrating the theory of turbulence
TL;DR: In this article, the application of statistical analysis and statistical mechanics to the problem of turbulent fluid motion has attracted much attention in recent years, and the authors investigated a complicated system of nonlinear equations, in order to find out enough about the properties of the solutions of these equations that insight can be obtained into the various patterns exhibited by the field and that data can be derived concerning the relative frequencies of these patterns in the hope that in this way a basis may be found for the calculation of important values.