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Journal ArticleDOI

The immune system, adaptation, and machine learning

TLDR
A dynamical model for the immune system is described that is based on the network hypothesis of Jerne, and is simple enough to simulate on a computer, and has a strong similarity to an approach to learning and artificial intelligence introduced by Holland, called the classifier system.
About
This article is published in Physica D: Nonlinear Phenomena.The article was published on 1986-10-01. It has received 1326 citations till now. The article focuses on the topics: Artificial immune system & Learning classifier system.

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Citations
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Proceedings ArticleDOI

An improved immune inspired hyper-heuristic for combinatorial optimisation problems

TL;DR: The mechanisms by which new heuristics are defined and subsequently generated are addressed, and a mutation-based operator inspired by clonal-selection is introduced to control the balance between exploration and exploitation in the generation of new network elements.
Proceedings ArticleDOI

Optimal switching placement for customer interruption cost minimization

TL;DR: In this article, the authors proposed the immune algorithm (IA) to derive the optimal placement of switching devices by minimizing the total cost of customer service outage and investment cost of line switches.
Book ChapterDOI

A New Bio-inspired Approach to the Traveling Salesman Problem

TL;DR: This paper proposes a novel mosquito host-seeking algorithm (MHSA) as a new branch of biology-inspired algorithms for solving TSP problems and presents the mathematical model, the algorithm, the motivation, and the biological model.
Journal Article

"Going back to our roots": second generation biocomputing

TL;DR: In this paper, the authors argue that the time has now come for a reassessment of how we exploit biology to generate new omputational systems, and that a new, inherently inter-disciplinary approach is needed for the development of the emerging "second generation " of bio-inspired methods.

A New Bio-inspired Approach to the Traveling Salesman Problem

TL;DR: In this paper, the authors proposed a new branch of biology-inspired algorithms for solving TSP problems, inspired by the host-seeking behavior of mosquitoes, which can work out the theoretical optimum solution, which is important and exciting, and give the theoretical foundation and present experiment results that verify this fact.
References
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Journal ArticleDOI

Somatic generation of antibody diversity

TL;DR: In the genome of a germ-line cell, the genetic information for an immunoglobulin polypeptide chain is contained in multiple gene segments scattered along a chromosome which are assembled by recombination which leads to the formation of a complete gene.
Book ChapterDOI

A mathematical model illustrating the theory of turbulence

TL;DR: In this article, the application of statistical analysis and statistical mechanics to the problem of turbulent fluid motion has attracted much attention in recent years, and the authors investigated a complicated system of nonlinear equations, in order to find out enough about the properties of the solutions of these equations that insight can be obtained into the various patterns exhibited by the field and that data can be derived concerning the relative frequencies of these patterns in the hope that in this way a basis may be found for the calculation of important values.