Journal ArticleDOI
The immune system, adaptation, and machine learning
TLDR
A dynamical model for the immune system is described that is based on the network hypothesis of Jerne, and is simple enough to simulate on a computer, and has a strong similarity to an approach to learning and artificial intelligence introduced by Holland, called the classifier system.About:
This article is published in Physica D: Nonlinear Phenomena.The article was published on 1986-10-01. It has received 1326 citations till now. The article focuses on the topics: Artificial immune system & Learning classifier system.read more
Citations
More filters
Multiple Attractor Cellular Automata (MACA) for Addressing Major Problems in Bioinformatics
TL;DR: In this paper, an automated procedure was proposed with MACA (Multiple Attractor Cellular Automata) which can address all these problems of bioinformatics like predicting the protein coding region, finding the promoter region, predicting the structure of protein and many other problems in bioInformatics.
Proceedings ArticleDOI
Anomaly detection inspired by immune network theory: A proposal
TL;DR: The requirements from a range of distributed autonomous systems are examined and then a novel unsupervised anomaly detection architecture capable of online adaptation inspired by the vertebrate immune system is proposed.
Journal ArticleDOI
Translatability and transferability of in silico models: Context of use switching to predict the effects of environmental chemicals on the immune system
TL;DR: In this paper , the Universal Immune System Simulator was used to simulate the effects of PFAS on the immune system, introducing entities and new interactions that are biologically involved in the phenomenon.
Book ChapterDOI
A computational model for the cognitive immune system theory based on learning classifier systems
TL;DR: This paper proposes a modification of the classic LCS that can be used for modelling the Cognitive Immune System Theory introduced by I. Cohen and introduces the representations of the immune agents, the interactions that take place among them and the applied evolutionary mechanisms.
Proceedings ArticleDOI
The Artificial Immune Systems Domain: Identifying Progress and Main Contributors Using Publication and Co-Authorship Analyses
TL;DR: In this paper, the authors apply social network analysis to the co-authorship network of the most comprehensive publicly accessible Artificial Immune System (AIS) bibliography, automatically extracting publication dates and author names from the bibliography and evaluate authors with the highest degree and influence.
References
More filters
Journal ArticleDOI
Somatic generation of antibody diversity
TL;DR: In the genome of a germ-line cell, the genetic information for an immunoglobulin polypeptide chain is contained in multiple gene segments scattered along a chromosome which are assembled by recombination which leads to the formation of a complete gene.
Book ChapterDOI
A mathematical model illustrating the theory of turbulence
TL;DR: In this article, the application of statistical analysis and statistical mechanics to the problem of turbulent fluid motion has attracted much attention in recent years, and the authors investigated a complicated system of nonlinear equations, in order to find out enough about the properties of the solutions of these equations that insight can be obtained into the various patterns exhibited by the field and that data can be derived concerning the relative frequencies of these patterns in the hope that in this way a basis may be found for the calculation of important values.