Journal ArticleDOI
The immune system, adaptation, and machine learning
TLDR
A dynamical model for the immune system is described that is based on the network hypothesis of Jerne, and is simple enough to simulate on a computer, and has a strong similarity to an approach to learning and artificial intelligence introduced by Holland, called the classifier system.About:
This article is published in Physica D: Nonlinear Phenomena.The article was published on 1986-10-01. It has received 1326 citations till now. The article focuses on the topics: Artificial immune system & Learning classifier system.read more
Citations
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Proceedings Article
Parametric optimization of storage systems
TL;DR: This work proposes using meta-heuristic techniques such as genetic algorithms to efficiently find nearoptimal configurations for storage systems, based on promising early results.
Book ChapterDOI
The abstract immune system algorithm
José Pacheco,José Félix Costa +1 more
TL;DR: This paper presents an Abstract Immune System Algorithm, based on the model introduced by Farmer et al, inspired on the theory of Clonal Selection and Idiotypic Network due to Niels Jerne.
Journal ArticleDOI
Quantifying the Protection of Activating and Inhibiting NK Cell Receptors during Infection with a CMV-Like Virus.
TL;DR: A probabilistic model is developed, which predicts the optimal specificity of inhibitory and activating NK cell receptors needed to offer the best protection against a CMV-like virus and quantifies the degree of protection of each receptor type.
Journal ArticleDOI
Distributed and autonomous sensing based on the immune network
TL;DR: A distributed and autonomous sensor network is proposed based on the informational features of the immune network: recognition of nonself by distributed and dynamically interacting units, recognition by a simple comparison with the units themselves, and dynamic propagation of activation that would lead to system-level recognition.
[IEEE 2013 First Iranian Conference on Pattern Recognition and Image Analysis (PRIA) - Birjand, Iran (2013.03.6-2013.03.8)] 2013 First Iranian Conference on Pattern Recognition and Image Analysis (PRIA) - Application of inclined planes system optimization on data clustering
TL;DR: A new clustering method based on the Inclined Planes system Optimization algorithm was proposed and evaluate on a series of standard datasets revealed a significant superiority over other similar clustering algorithms.
References
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Journal ArticleDOI
Somatic generation of antibody diversity
TL;DR: In the genome of a germ-line cell, the genetic information for an immunoglobulin polypeptide chain is contained in multiple gene segments scattered along a chromosome which are assembled by recombination which leads to the formation of a complete gene.
Book ChapterDOI
A mathematical model illustrating the theory of turbulence
TL;DR: In this article, the application of statistical analysis and statistical mechanics to the problem of turbulent fluid motion has attracted much attention in recent years, and the authors investigated a complicated system of nonlinear equations, in order to find out enough about the properties of the solutions of these equations that insight can be obtained into the various patterns exhibited by the field and that data can be derived concerning the relative frequencies of these patterns in the hope that in this way a basis may be found for the calculation of important values.