Journal ArticleDOI
The immune system, adaptation, and machine learning
TLDR
A dynamical model for the immune system is described that is based on the network hypothesis of Jerne, and is simple enough to simulate on a computer, and has a strong similarity to an approach to learning and artificial intelligence introduced by Holland, called the classifier system.About:
This article is published in Physica D: Nonlinear Phenomena.The article was published on 1986-10-01. It has received 1326 citations till now. The article focuses on the topics: Artificial immune system & Learning classifier system.read more
Citations
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Book ChapterDOI
A Paratope Is Not an Epitope: Implications for Immune Network Models and Clonal Selection
TL;DR: A theoretical generic immune network (GIN) is presented, that can be used to explore the network dynamics of several families of different B-cell representations at the same time, and that combines features of clonal selection and immune networks in a single model.
FOA: ‘Following’ Optimization Algorithm for solving Power engineering optimization problems
TL;DR: A new approach of applying optimization-based social relationships among the members of a community is investigated and FOA is able to provide better results as compared to the other well-known optimization algorithms.
Journal ArticleDOI
Timely HAART initiation may pave the way for a better viral control
TL;DR: A timing threshold is identified, corresponding to approximately three weeks post-infection, after which the capability to control HIV replication is lost and HAART initiation occurring within three weeks from the infection could allow to preserve a significant control capability.
Proceedings ArticleDOI
Multiple-valued immune network model and its simulations
TL;DR: The model of multiple-valued immune network is formulated based on the analogy with the interaction between B cells and T cells in immune system and has a property that resembles immune response quite well.
Journal ArticleDOI
Autopoiesis, the immune system, and adaptive information filtering
Nikolaos Nanas,Anne De Roeck +1 more
TL;DR: Nootropia, a model inspired by the autopoietic view of the immune system that reacts to user feedback in order to define and preserve the user interests, is described in the context of adaptive, content-based document filtering and evaluated using virtual users.
References
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Journal ArticleDOI
Somatic generation of antibody diversity
TL;DR: In the genome of a germ-line cell, the genetic information for an immunoglobulin polypeptide chain is contained in multiple gene segments scattered along a chromosome which are assembled by recombination which leads to the formation of a complete gene.
Book ChapterDOI
A mathematical model illustrating the theory of turbulence
TL;DR: In this article, the application of statistical analysis and statistical mechanics to the problem of turbulent fluid motion has attracted much attention in recent years, and the authors investigated a complicated system of nonlinear equations, in order to find out enough about the properties of the solutions of these equations that insight can be obtained into the various patterns exhibited by the field and that data can be derived concerning the relative frequencies of these patterns in the hope that in this way a basis may be found for the calculation of important values.