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Open AccessJournal ArticleDOI

What’s normal? Oligosaccharide concentrations and profiles in milk produced by healthy women vary geographically

TLDR
The hypothesis that normal HMO concentrations and profiles vary geographically, even in healthy women is supported and targeted genomic analyses are required to determine whether these differences are due at least in part to genetic variation.
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This article is published in The American Journal of Clinical Nutrition.The article was published on 2017-05-01 and is currently open access. It has received 263 citations till now. The article focuses on the topics: Postpartum period.

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DissertationDOI

Cross-feeding interactions of gut symbionts driven by human milk oligosaccharidesand mucins

Loo Wee Chia
TL;DR: The molecular mechanisms of glycan-foraging by key microbial species and the potential butyrate-inducing interaction among gut symbionts is presented and it is shown that Bacteroides thetaiotaomicron could drive the butyrogenic trophic chain with Anaerostipes caccae.
Journal ArticleDOI

In vitro fermentation of fructooligosaccharide and galactooligosaccharide and their effects on gut microbiota and SCFAs in infants

TL;DR: In this paper , the fermentation characteristics of fructooligosaccharides (FOS) and galactooligous (GOS) with infant fecal inoculum were investigated by HPLC and the changes in short-chain fatty acids (SCFAs) and lactate production were monitored.
Journal ArticleDOI

A safety evaluation of mixed human milk oligosaccharides in neonatal farm piglets

Paul R Hanlon
TL;DR: The safety of this ingredient for addition to infant formula products is supported, since administration of HMO MIX 1 in a liquid diet up to 8.0 g/L resulted in no toxicologically-relevant effects in comparison with animals fed a control diet.
Journal ArticleDOI

Role of milk glycome in prevention, treatment, and recovery of COVID-19

TL;DR: In this paper , the authors discuss the recent clinical studies and potential mechanisms of free and conjugated glycans' role in the prevention, treatment, and recovery of COVID-19.
References
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Journal Article

R: A language and environment for statistical computing.

R Core Team
- 01 Jan 2014 - 
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
Journal ArticleDOI

Controlling the false discovery rate: a practical and powerful approach to multiple testing

TL;DR: In this paper, a different approach to problems of multiple significance testing is presented, which calls for controlling the expected proportion of falsely rejected hypotheses -the false discovery rate, which is equivalent to the FWER when all hypotheses are true but is smaller otherwise.
Book

ggplot2: Elegant Graphics for Data Analysis

TL;DR: This book describes ggplot2, a new data visualization package for R that uses the insights from Leland Wilkisons Grammar of Graphics to create a powerful and flexible system for creating data graphics.
Journal ArticleDOI

Metagenes and molecular pattern discovery using matrix factorization.

TL;DR: Nonnegative matrix factorization is described, an algorithm based on decomposition by parts that can reduce the dimension of expression data from thousands of genes to a handful of metagenes, and found less sensitive to a priori selection of genes or initial conditions and able to detect alternative or context-dependent patterns of gene expression in complex biological systems.
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