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Open AccessJournal ArticleDOI

What’s normal? Oligosaccharide concentrations and profiles in milk produced by healthy women vary geographically

TLDR
The hypothesis that normal HMO concentrations and profiles vary geographically, even in healthy women is supported and targeted genomic analyses are required to determine whether these differences are due at least in part to genetic variation.
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This article is published in The American Journal of Clinical Nutrition.The article was published on 2017-05-01 and is currently open access. It has received 263 citations till now. The article focuses on the topics: Postpartum period.

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Citations
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Journal ArticleDOI

Food Insecurity and Maternal Diet Influence Human Milk Composition between the Infant’s Birth and 6 Months after Birth in Central-Africa

TL;DR: Food insecurity and maternal diet had a meaningful effect on HM composition with a possible impact being an infant undernourishment risk and plead for consistent actions on food security as an effective manner to influence the nutritional content of HM and thereby, potentially improve infant survival and healthy growth.
Journal ArticleDOI

Human Milk Oligosaccharides Are Present in Amniotic Fluid and Show Specific Patterns Dependent on Gestational Age

TL;DR: HMOs are already present in AF early in pregnancy, suggesting roles for HMOs in fetal tissue development during the time course of pregnancy, and extensive contact of the fetus with a broad variety of H MOs is demonstrated.
Journal ArticleDOI

Human milk nutritional composition across lactational stages in Central Africa

TL;DR: In this article , the authors conducted a cohort study among 48 Central-African women and their 50 infants to analyze the emergence of gut dysbiosis in infants and describe the mother-infant transmission of microbiota between birth and 6 months of age.
Book ChapterDOI

Immune factors in human milk

TL;DR: Although the actual physiologic effects of each of these factors in the infant have not yet been elucidated completely, their presence seems to be extraordinarily relevant for infant and mammary health.
Posted ContentDOI

Rapid changes in Atlantic grey seal milk from birth to desertion

TL;DR: Milk was collected from Atlantic grey seals periodically from birth until near desertion, indicating the most rapid transition from colostrum to mature phase lactation yet observed, and there was an unexpected persistence of immunoglobulin G almost until weaning, potentially indicating prolonged trans-intestinal transfer of IgG.
References
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Journal Article

R: A language and environment for statistical computing.

R Core Team
- 01 Jan 2014 - 
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
Journal ArticleDOI

Controlling the false discovery rate: a practical and powerful approach to multiple testing

TL;DR: In this paper, a different approach to problems of multiple significance testing is presented, which calls for controlling the expected proportion of falsely rejected hypotheses -the false discovery rate, which is equivalent to the FWER when all hypotheses are true but is smaller otherwise.
Book

ggplot2: Elegant Graphics for Data Analysis

TL;DR: This book describes ggplot2, a new data visualization package for R that uses the insights from Leland Wilkisons Grammar of Graphics to create a powerful and flexible system for creating data graphics.
Journal ArticleDOI

Metagenes and molecular pattern discovery using matrix factorization.

TL;DR: Nonnegative matrix factorization is described, an algorithm based on decomposition by parts that can reduce the dimension of expression data from thousands of genes to a handful of metagenes, and found less sensitive to a priori selection of genes or initial conditions and able to detect alternative or context-dependent patterns of gene expression in complex biological systems.
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