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Open AccessJournal ArticleDOI

What’s normal? Oligosaccharide concentrations and profiles in milk produced by healthy women vary geographically

TLDR
The hypothesis that normal HMO concentrations and profiles vary geographically, even in healthy women is supported and targeted genomic analyses are required to determine whether these differences are due at least in part to genetic variation.
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This article is published in The American Journal of Clinical Nutrition.The article was published on 2017-05-01 and is currently open access. It has received 263 citations till now. The article focuses on the topics: Postpartum period.

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Gut microbiota alterations and dietary modulation in childhood malnutrition - The role of short chain fatty acids.

TL;DR: The gut microbiota development in the early life, gut microbiota alterations in childhood undernutrition and obesity, and whether this relationship is causal are outlined and the potential of probiotics, prebiotics and synbiotics for modulating the gut microbiota during childhood as a prevention and treatment strategy against under malnutrition and obesity is discussed.
Journal ArticleDOI

Human Milk Oligosaccharides in Colostrum and Mature Milk of Chinese Mothers: Lewis Positive Secretor Subgroups

TL;DR: This study showed that total HMO concentrations in Chinese human milk decreased significantly over a 20-wk lactation period, independent of the mother’s SeLe status, although with individual variations.
Journal ArticleDOI

Priming for Life: Early Life Nutrition and the Microbiota-Gut-Brain Axis

TL;DR: A review of early life nutrition and microbiota priming of important bodily systems and all the factors influencing the microbial coexistence with the host during early life development is presented in this article.
Journal ArticleDOI

Maternal and Infant Factors Associated with Human Milk Oligosaccharides Concentrations According to Secretor and Lewis Phenotypes.

TL;DR: Unprecedented data on HMOs concentrations from breastfeeding Brazilian women and novel associations of maternal allergic disease and infant’s sex with H MOs concentrations are presented.
Journal ArticleDOI

The Mean of Milk: A Review of Human Milk Oligosaccharide Concentrations throughout Lactation.

TL;DR: In this paper, the authors assess and rank human milk oligosaccharides (HMOs) from healthy mothers throughout lactation at a global level, using data from pooled (secretor and non-secretor) human milk samples.
References
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Journal Article

R: A language and environment for statistical computing.

R Core Team
- 01 Jan 2014 - 
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
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Controlling the false discovery rate: a practical and powerful approach to multiple testing

TL;DR: In this paper, a different approach to problems of multiple significance testing is presented, which calls for controlling the expected proportion of falsely rejected hypotheses -the false discovery rate, which is equivalent to the FWER when all hypotheses are true but is smaller otherwise.
Book

ggplot2: Elegant Graphics for Data Analysis

TL;DR: This book describes ggplot2, a new data visualization package for R that uses the insights from Leland Wilkisons Grammar of Graphics to create a powerful and flexible system for creating data graphics.
Journal ArticleDOI

Metagenes and molecular pattern discovery using matrix factorization.

TL;DR: Nonnegative matrix factorization is described, an algorithm based on decomposition by parts that can reduce the dimension of expression data from thousands of genes to a handful of metagenes, and found less sensitive to a priori selection of genes or initial conditions and able to detect alternative or context-dependent patterns of gene expression in complex biological systems.
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