What’s normal? Oligosaccharide concentrations and profiles in milk produced by healthy women vary geographically
Michelle K. McGuire,Courtney L. Meehan,Mark A. McGuire,Janet E. Williams,James A. Foster,Daniel W. Sellen,Elizabeth W. Kamau-Mbuthia,Egidioh W. Kamundia,Samwel Mbugua,Sophie E. Moore,Andrew M. Prentice,Linda J. Kvist,Gloria E. Otoo,Sarah L Brooker,William J. Price,Bahman Shafii,Caitlyn D. Placek,Kimberly A. Lackey,Bianca Robertson,Susana Manzano,Lorena Ruiz,Juan M. Rodríguez,Rossina G. Pareja,Lars Bode +23 more
TLDR
The hypothesis that normal HMO concentrations and profiles vary geographically, even in healthy women is supported and targeted genomic analyses are required to determine whether these differences are due at least in part to genetic variation.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2017-05-01 and is currently open access. It has received 263 citations till now. The article focuses on the topics: Postpartum period.read more
Citations
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Safety of 2'-fucosyllactose/difucosyllactose mixture as a novel food pursuant to Regulation (EU) 2015/2283.
TL;DR: In this paper, the authors present Davide Arcella for the support provided to this scientific opinion, and the panel wishes to thank DavideArcella and his colleagues for their support.
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The association of human milk oligosaccharides with glucose metabolism in overweight and obese pregnant women
Evelyn Jantscher-Krenn,Carmen Treichler,Waltraud Brandl,Lukas Schönbacher,Harald Köfeler,Mireille N M van Poppel +5 more
TL;DR: The sialylated HMOs 3'SL and3'SLN was more predictive of future GDM diagnoses than was fasting glucose in early pregnancy; LDFT was associated with fasting insulin and HOMA-index.
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Perspective: Human Milk Oligosaccharides: Fuel for Childhood Obesity Prevention?
TL;DR: Although it seems that HMOs might have a role in infant growth and adiposity, there is not enough consistent evidence to understand their potential role in obesity prevention.
Journal ArticleDOI
Variation in Human Milk Composition Is Related to Differences in Milk and Infant Fecal Microbial Communities.
Ryan M. Pace,Janet E. Williams,Bianca Robertson,Kimberly A. Lackey,Courtney L. Meehan,William J. Price,James A. Foster,Daniel W. Sellen,Elizabeth W. Kamau-Mbuthia,Egidioh W. Kamundia,Samwel Mbugua,Sophie E. Moore,Andrew M. Prentice,Debela G. Kita,Linda J. Kvist,Gloria E. Otoo,Lorena Ruiz,Juan M. Rodríguez,Rossina G. Pareja,Mark A. McGuire,Lars Bode,Michelle K. McGuire +21 more
TL;DR: In this article, the authors characterized and contrasted concentrations of milk-borne lactose, protein, and HMOs and examined their associations with milk and infant fecal microbiomes in samples collected in 11 geographically diverse sites.
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Capillary Electrophoresis Analysis of Bovine Milk Oligosaccharides Permits an Assessment of the Influence of Diet and the Discovery of Nine Abundant Sulfated Analogues.
TL;DR: To test the hypothesis that the bovine diet may lead to changes in relative BMO abundances, a rapid capillary electrophoresis (CE)-based work flow was developed to profile the BMOs extracted from the milk of cows fed distinctly different diets.
References
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