What’s normal? Oligosaccharide concentrations and profiles in milk produced by healthy women vary geographically
Michelle K. McGuire,Courtney L. Meehan,Mark A. McGuire,Janet E. Williams,James A. Foster,Daniel W. Sellen,Elizabeth W. Kamau-Mbuthia,Egidioh W. Kamundia,Samwel Mbugua,Sophie E. Moore,Andrew M. Prentice,Linda J. Kvist,Gloria E. Otoo,Sarah L Brooker,William J. Price,Bahman Shafii,Caitlyn D. Placek,Kimberly A. Lackey,Bianca Robertson,Susana Manzano,Lorena Ruiz,Juan M. Rodríguez,Rossina G. Pareja,Lars Bode +23 more
TLDR
The hypothesis that normal HMO concentrations and profiles vary geographically, even in healthy women is supported and targeted genomic analyses are required to determine whether these differences are due at least in part to genetic variation.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2017-05-01 and is currently open access. It has received 263 citations till now. The article focuses on the topics: Postpartum period.read more
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Book ChapterDOI
Prebiotics and Human Milk Oligosaccharides
TL;DR: Current understanding of prebiotics and human milk oligosaccharides is reviewed to determine whether these structures and function relevant in specific disease states are still unclear.
Journal ArticleDOI
Microbiomes and Childhood Malnutrition: What Is the Evidence?
TL;DR: There is growing evidence of a bidirectional association between variation in the gastrointestinal (GI) microbiome and risk of/resilience to malnutrition during early life as discussed by the authors, and the putative impact of GI microbiomes on malnutrition is likely modified by a variety of important variables such as genetics, environmental pathogen exposure and its timing, dietary factors, and cultural/societal pattern (e.g., use of antibiotics).
Journal ArticleDOI
Prebiotic components of breast milk and the possibility of repeating their effects in infant formulas
TL;DR: The role of prebiotics in breast milk and infant formula is described for the formation and maintenance of a healthy baby intestinal microbiota, which is a key element in the formation of normal digestion, a functionally sound immune system and metabolism.
Journal ArticleDOI
Safety of 2′‐fucosyllactose (2’‐FL) produced by a derivative strain (APC199) of Corynebacterium glutamicum ATCC 13032 as a novel food pursuant to Regulation (EU) 2015/2283
Dominique Turck,Torsten Bohn,J.J.M. Castenmiller,Stefaan De Henauw,Karen I. Hirsch-Ernst,Alexandre Maciuk,Inge Mangelsdorf,Harry J. McArdle,Androniki Naska,Carmen Peláez,Kristina Pentieva,Alfonso Siani,Frank Thies,Sophia Tsabouri,Marco Vinceti,Francesco Cubadda,Thomas Frenzel,Marina Heinonen,Rosangela Marchelli,Monika Neuhäuser-Berthold,Morten Poulsen,Miguel Prieto Maradona,Josef Rudolf Schlatter,Henk Van Loveren,Paolo Colombo,Estefania Noriega Fernandez,Helle Katrine Knutsen +26 more
TL;DR: In this article , the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) delivered an opinion on 2'fucosyllactose (2'FL) as a novel food (NF) pursuant to Regulation (EU) 2015/2283.
Journal ArticleDOI
Determining the metabolic fate of human milk oligosaccharides: It may just be more complex than you think?
TL;DR: Results indicated that, compared with the breastfed reference group, the HMO-containing formula stimulated increases in Bifidobacterium, albeit to a lower degree than the reference breastfed group, and help to explain the large variability in the presence and levels of HMOs detected in the faecal samples of infants.
References
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